Gene Symbol | TSPYL5 |
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Entrez Gene | 85453 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | TSPY-like 5 |
Other Description | TSPY-like protein 5|testis-specific Y-encoded-like protein 5 |
Swissprots | Q86VY4 Q9C0B3 B3KRF0 |
Accessions | EAW91759 Q86VY4 AB051537 BAB21841 AK091445 BAG52362 AK092272 AL080059 BC045630 AAH45630 HQ448496 ADQ32976 NM_033512 NP_277047 |
Function | Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7. {ECO:0000269|PubMed:20079711, ECO:0000269|PubMed:21170034}. |
TSPYL5 CRISPR/Cas9 KO Plasmid (h) - sc-403934 from Santa Cruz Biotechnology
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TSPYL5 HDR Plasmid (h) - sc-403934-HDR from Santa Cruz Biotechnology
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TSPYL5 Double Nickase Plasmid (h) - sc-403934-NIC from Santa Cruz Biotechnology
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TSPYL5 Double Nickase Plasmid (h2) - sc-403934-NIC-2 from Santa Cruz Biotechnology
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TSPYL5 CRISPR Activation Plasmid (h) - sc-403934-ACT from Santa Cruz Biotechnology
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TSPYL5 CRISPR Activation Plasmid (h2) - sc-403934-ACT-2 from Santa Cruz Biotechnology
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TSPYL5 Lentiviral Activation Particles (h) - sc-403934-LAC from Santa Cruz Biotechnology
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TSPYL5 Lentiviral Activation Particles (h2) - sc-403934-LAC-2 from Santa Cruz Biotechnology
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TSPYL5 siRNA (h) - sc-77735 from Santa Cruz Biotechnology
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TSPYL5 shRNA Plasmid (h) - sc-77735-SH from Santa Cruz Biotechnology
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TSPYL5 shRNA (h) Lentiviral Particles - sc-77735-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU046361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22133 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22133 from Sigma-Aldrich
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TSPYL5 siRNA (Human) - CRJ3820 from Cohesion Biosciences
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TSPYL5 - MBS8207219 from MyBioSource
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shRNA set against Human TSPYL5 (NM_033512.2) - SHH436544 from Creative biogene
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TSPYL5 shRNA Plasmid (Human) - CHJ3820 from Cohesion Biosciences
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TSPYL5 miRNA 3'UTR clone - MiUTR1H-10832 from Creative biogene
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