| Gene Symbol |
NEBL
|
| Entrez Gene |
10529
|
| Alt Symbol |
LASP2, LNEBL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nebulette
|
| Other Description |
LIM-nebulette|actin-binding Z-disk protein
|
| Swissprots |
Q9UIC4 O76041 Q70I54 Q2TBD0 B0YJ45
|
| Accessions |
ACA06021 ACA06022 ACA06023 ACA06024 ACA06025 ACA06026 EAW86172 EAW86175 O76041 AB209311 BAD92548 AJ580772 CAE45323 AK096540 BAC04812 AK294926 BAG58008 AK295186 BAG58190 AK316521 BAH14892 BC110452 AAI10453 BC110453 AAI10454 BC126132 AAI26133 BC126134 AAI26135 BC144201 BI522541 BM973051 CR744526 DT220372 Y16241 CAA76130 Y17673 CAA76810 XM_005252342 XP_005252399 XM_005252343 XP_005252400 XM_005252344 XP_005252401 XM_011519290 XP_011517592 XM_011519291 XP_011517593 XR_242691 NM_001173484 NP_001166955 NM_006393 NP_006384 NM_213569 NP_998734 NM_016365
|
| Function |
Binds to actin and plays an important role in the assembly of the Z-disk. Isoform 2 might play a role in the assembly of focal adhesion. {ECO:0000269|PubMed:15004028}.
|
| Subcellular Location |
Isoform 2: Cytoplasm {ECO:0000269|PubMed:15004028}.
|
| Tissue Specificity |
Abundantly expressed in cardiac muscle, but not in skeletal or smooth muscle. Localized to Z-lines in cardiac cells and to dense bodies in nonmuscle cells. Isoform 2 is expressed in non-muscle cells such as in fibroblasts.
|