| Gene Symbol | TAT |
|---|---|
| Entrez Gene | 6898 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | tyrosine aminotransferase |
| Other Description | L-tyrosine:2-oxoglutarate aminotransferase|tyrosine aminotransferase, cytosolic |
| Swissprots | B2R8I1 P17735 D3DWS2 |
| Accessions | CAA36749 EAW59230 EAW59231 P17735 AK313380 BAG36178 BC020707 AAH20707 BC022292 BC130534 AAI30535 HQ258233 ADR82987 X52520 CAA36750 X55675 CAA39210 NM_000353 NP_000344 |
| Function | Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine. {ECO:0000269|PubMed:16640556, ECO:0000269|PubMed:7999802}. |
| Top Pathways | Ubiquinone and other terpenoid-quinone biosynthesis, Cysteine and methionine metabolism, Phenylalanine metabolism, Tyrosine metabolism, Biosynthesis of amino acids |