| Gene Symbol |
TAT
|
| Entrez Gene |
6898
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tyrosine aminotransferase
|
| Other Description |
L-tyrosine:2-oxoglutarate aminotransferase|tyrosine aminotransferase, cytosolic
|
| Swissprots |
B2R8I1 P17735 D3DWS2
|
| Accessions |
CAA36749 EAW59230 EAW59231 P17735 AK313380 BAG36178 BC020707 AAH20707 BC022292 BC130534 AAI30535 HQ258233 ADR82987 X52520 CAA36750 X55675 CAA39210 NM_000353 NP_000344
|
| Function |
Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine. {ECO:0000269|PubMed:16640556, ECO:0000269|PubMed:7999802}.
|
| Top Pathways |
Ubiquinone and other terpenoid-quinone biosynthesis, Cysteine and methionine metabolism, Phenylalanine metabolism, Tyrosine metabolism, Biosynthesis of amino acids
|