Gene Symbol | TBCC |
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Entrez Gene | 6903 |
Alt Symbol | CFC |
Species | Human |
Gene Type | protein-coding |
Description | tubulin folding cofactor C |
Other Description | tubulin-folding cofactor C|tubulin-specific chaperone C |
Swissprots | Q53Y43 Q15814 Q5T787 |
Accessions | EAX04100 Q15814 AK312681 BAG35561 BC017479 AAH17479 BC020170 AAH20170 BE795945 BT007002 AAP35648 JF432875 ADZ16092 U61234 AAB17539 NM_003192 NP_003183 |
Function | Tubulin-folding protein; involved in the final step of the tubulin folding pathway. {ECO:0000269|PubMed:11847227}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12417528}. Note=Detected predominantly in the photoreceptor connecting cilium. |
Tissue Specificity | Expressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecting cilium at the tips of the IS (at protein level). {ECO:0000269|PubMed:12417528}. |
TBCC CRISPR/Cas9 KO Plasmid (h) - sc-410548 from Santa Cruz Biotechnology
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TBCC HDR Plasmid (h) - sc-410548-HDR from Santa Cruz Biotechnology
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TBCC Double Nickase Plasmid (h) - sc-410548-NIC from Santa Cruz Biotechnology
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TBCC Double Nickase Plasmid (h2) - sc-410548-NIC-2 from Santa Cruz Biotechnology
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TBCC CRISPR Activation Plasmid (h) - sc-410548-ACT from Santa Cruz Biotechnology
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TBCC CRISPR Activation Plasmid (h2) - sc-410548-ACT-2 from Santa Cruz Biotechnology
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TBCC Lentiviral Activation Particles (h) - sc-410548-LAC from Santa Cruz Biotechnology
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TBCC Lentiviral Activation Particles (h2) - sc-410548-LAC-2 from Santa Cruz Biotechnology
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TBCC siRNA (h) - sc-95496 from Santa Cruz Biotechnology
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TBCC shRNA Plasmid (h) - sc-95496-SH from Santa Cruz Biotechnology
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TBCC shRNA (h) Lentiviral Particles - sc-95496-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU035681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21085 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21085 from Sigma-Aldrich
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TBCC siRNA (Human) - CRH4729 from Cohesion Biosciences
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TBCC RNAi - H00006903-R01 from Novus Biologicals
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TBCC - MBS8237337 from MyBioSource
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shRNA set against Human TBCC (NM_003192.2) - SHH424120 from Creative biogene
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shRNA set against Human TBCC(NM_003192.2) - SHL041642 from Creative biogene
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TBCC shRNA Plasmid (Human) - CHH4729 from Cohesion Biosciences
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TBCC miRNA 3'UTR clone - MiUTR1H-10230 from Creative biogene
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