| Gene Symbol |
PTPRO
|
| Entrez Gene |
5800
|
| Alt Symbol |
GLEPP1, NPHS6, PTP-OC, PTP-U2, PTPROT, PTPU2, R-PTP-O
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein tyrosine phosphatase, receptor type, O
|
| Other Description |
PTP phi|PTPase U2|glomerular epithelial protein 1|osteoclastic transmembrane protein-tyrosine phosphatase|phosphotyrosine phosphatase U2|protein tyrosine phosphatase PTP-U2|receptor-type tyrosine-protein phosphatase O
|
| Swissprots |
Q13101 Q9UBF0 Q16827 Q9UBT5 Q8IYG3 A0AV39
|
| Accessions |
EAW96348 EAW96349 EAW96350 EAW96351 EAW96352 EAW96353 Q16827 AB209729 BAD92966 AF152378 AAD55680 AF187042 AAF04085 AF187043 AAF04086 AF187044 AAF04087 AK289784 BAF82473 AK290982 BAF83671 AK299529 BAG61478 BC035960 AAH35960 BC126201 AAI26202 BC126203 AAI26204 DA165109 DC358516 DR000351 U20489 AAA82892 Z48541 CAA88425 XM_011520792 XP_011519094 XR_931316 XR_931317 XR_931318 NM_002848 NP_002839 NM_030667 NP_109592 NM_030668 NP_109593 NM_030669 NP_109594 NM_030670 NP_109595 NM_030671 NP_109596
|
| Function |
Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Glomerulus of kidney. Also detected in brain, lung and placenta. {ECO:0000269|PubMed:10498613}.
|