Gene Symbol | P2RY14 |
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Entrez Gene | 9934 |
Alt Symbol | BPR105, GPR105, P2Y14 |
Species | Human |
Gene Type | protein-coding |
Description | purinergic receptor P2Y, G-protein coupled, 14 |
Other Description | G protein coupled receptor for UDP-glucose|G protein-coupled receptor 105|G-protein coupled receptor 105|P2Y purinoceptor 14|P2Y(14) receptor|P2Y14 receptor|UDP-glucose receptor |
Swissprots | Q15391 Q8IYT7 |
Accessions | AAL47764 CAJ33692 EAW78809 EAW78810 Q15391 AK289617 BAF82306 BC034989 AAH34989 CD110153 D13626 BAA02791 EF577400 ABQ52420 XM_005247922 XP_005247979 XM_005247923 XP_005247980 XM_011513340 XP_011511642 NM_001081455 NP_001074924 NM_014879 NP_055694 |
Function | Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP. {ECO:0000269|PubMed:10753868}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney. |
Top Pathways | Neuroactive ligand-receptor interaction |
GPR105 CRISPR/Cas9 KO Plasmid (h) - sc-405954 from Santa Cruz Biotechnology
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GPR105 HDR Plasmid (h) - sc-405954-HDR from Santa Cruz Biotechnology
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GPR105 Double Nickase Plasmid (h) - sc-405954-NIC from Santa Cruz Biotechnology
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GPR105 Double Nickase Plasmid (h2) - sc-405954-NIC-2 from Santa Cruz Biotechnology
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GPR105 CRISPR Activation Plasmid (h) - sc-405954-ACT from Santa Cruz Biotechnology
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GPR105 CRISPR Activation Plasmid (h2) - sc-405954-ACT-2 from Santa Cruz Biotechnology
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GPR105 Lentiviral Activation Particles (h) - sc-405954-LAC from Santa Cruz Biotechnology
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GPR105 Lentiviral Activation Particles (h2) - sc-405954-LAC-2 from Santa Cruz Biotechnology
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GPR105 siRNA (h) - sc-60731 from Santa Cruz Biotechnology
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GPR105 shRNA Plasmid (h) - sc-60731-SH from Santa Cruz Biotechnology
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GPR105 shRNA (h) Lentiviral Particles - sc-60731-V from Santa Cruz Biotechnology
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P2Y14/GPR105 RNAi - H00009934-R02 from Novus Biologicals
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MISSION® esiRNA - EHU044661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16235 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16235 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08797 from Sigma-Aldrich
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P2RY14 siRNA (Human) - CRH6676 from Cohesion Biosciences
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GPR105 CRISPR/Cas9 KO Plasmid (h2) - sc-405954-KO-2 from Santa Cruz Biotechnology
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GPR105 HDR Plasmid (h2) - sc-405954-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human P2RY14 (NM_014879.3) - SHH369576 from Creative biogene
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shRNA set against Human P2RY14(NM_001081455.1) - SHR085524 from Creative biogene
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P2RY14 shRNA Plasmid (Human) - CHH6676 from Cohesion Biosciences
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P2RY14 miRNA 3'UTR clone - MiUTR1H-07445 from Creative biogene
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P2RY14 miRNA 3'UTR clone - MiUTR3H-11041 from Creative biogene
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