| Gene Symbol | KIFC3 |
|---|---|
| Entrez Gene | 3801 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | kinesin family member C3 |
| Other Description | kinesin-like protein KIFC3 |
| Swissprots | Q96HW6 Q49AQ0 Q49A29 O75299 B7Z484 Q9BVG8 A8K6S2 Q59G19 Q8IUT3 |
| Accessions | EAW82953 EAW82954 EAW82955 EAW82956 Q9BVG8 AB209290 BAD92527 AF004426 AAC24153 AK091891 AK092013 AK291737 BAF84426 AK295926 BAH12222 AK296995 BAH12470 AK299431 BAH13030 AK302743 BAH13794 AK303021 BAH13882 AK304132 BAH14114 AK307846 BC001211 AAH01211 BC008014 AAH08014 BC019057 BC034234 AAH34234 BC041132 AAH41132 BC047051 AAH47051 BX647698 CAI46023 DA989120 DC381406 DQ426879 ABD90538 DQ426880 ABD90539 DQ891857 ABM82783 DQ895046 ABM85972 XM_005255937 XP_005255994 XM_005255944 XP_005256001 XM_006721188 XP_006721251 XM_011523070 XP_011521372 XM_011523071 XP_011521373 XM_011523072 XP_011521374 XM_011523073 XP_011521375 XM_011523074 XP_011521376 XM_011523075 XP_011521377 XM_011523076 XP_011521378 XM_011523077 XP_011521379 XM_011523078 XP_011521380 XM_011523079 XP_011521381 XM_011523080 XP_011521382 NM_001130099 NP_001123571 NM_001130100 NP_001123572 NM_005550 NP_005541 |
| Function | Minus-end microtubule-dependent motor protein. Involved in apically targeted transport (By similarity). Required for zonula adherens maintenance. {ECO:0000250, ECO:0000269|PubMed:19041755}. |
| Subcellular Location | Cell junction, adherens junction {ECO:0000269|PubMed:19041755}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:19041755}. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Apical cell membrane. On membrane organelles immediately beneath the apical plasma membrane of renal tubular epithelial cells. Localized in the distal tubules and loops of Henle in the kidney, but not in the proximal tubules or the glomeruli, with stronger staining in the apical area of these epithelial cells (By similarity). Localizes along zonula adherens only at mature cell- cell contacts. {ECO:0000250}. |
KIFC3 CRISPR/Cas9 KO Plasmid (h) - sc-408746 from Santa Cruz Biotechnology
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KIFC3 HDR Plasmid (h) - sc-408746-HDR from Santa Cruz Biotechnology
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KIFC3 Double Nickase Plasmid (h) - sc-408746-NIC from Santa Cruz Biotechnology
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KIFC3 Double Nickase Plasmid (h2) - sc-408746-NIC-2 from Santa Cruz Biotechnology
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KIFC3 CRISPR Activation Plasmid (h) - sc-408746-ACT from Santa Cruz Biotechnology
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KIFC3 CRISPR Activation Plasmid (h2) - sc-408746-ACT-2 from Santa Cruz Biotechnology
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KIFC3 Lentiviral Activation Particles (h) - sc-408746-LAC from Santa Cruz Biotechnology
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KIFC3 Lentiviral Activation Particles (h2) - sc-408746-LAC-2 from Santa Cruz Biotechnology
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KIFC3 siRNA (h) - sc-93395 from Santa Cruz Biotechnology
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KIFC3 shRNA Plasmid (h) - sc-93395-SH from Santa Cruz Biotechnology
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KIFC3 shRNA (h) Lentiviral Particles - sc-93395-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11213 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11213 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05730 from Sigma-Aldrich
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KIFC3 siRNA (Human) - CRH2572 from Cohesion Biosciences
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shRNA set against Human KIFC3 (NM_005550.3) - SHH325451 from Creative biogene
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shRNA set against Human KIFC3(NM_005550.3) - SHL197946 from Creative biogene
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Human KIFC3 siRNA - orb263074 from Biorbyt
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KIFC3 shRNA Plasmid (Human) - CHH2572 from Cohesion Biosciences
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KIFC3 miRNA 3'UTR clone - MiUTR1H-05320 from Creative biogene
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KIFC3 miRNA 3'UTR clone - MiUTR3H-06894 from Creative biogene
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KIFC3 miRNA 3'UTR clone - MiUTR3H-06895 from Creative biogene
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