| Gene Symbol |
CYB561A3
|
| Entrez Gene |
220002
|
| Alt Symbol |
CYBASC3, LCYTB
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome b561 family, member A3
|
| Other Description |
cytochrome b ascorbate-dependent protein 3|cytochrome b, ascorbate dependent 3|cytochrome b561 family member A3|lysosomal cytochrome b
|
| Swissprots |
Q6PK96 Q8NBI2 J3KQH4 B4DLN9 B3KPU2
|
| Accessions |
EAW73941 EAW73942 Q8NBI2 AA085565 AI813810 AK024953 AK025870 AK056751 BAG51804 AK075559 BAC11698 AK097043 AK225754 AK297063 BAG59584 AK297084 BAG59601 AK310167 AK310976 AL833374 BC004391 AAH04391 BC014045 AAH14045 BC047710 AAH47710 BM692535 BP296553 BP366144 BP396674 CF125719 CF541093 DA948287 DC378209 DC389589 XM_011544821 XP_011543123 XM_011544822 XP_011543124 XM_011544823 XP_011543125 XM_011544824 XP_011543126 XM_011544825 XP_011543127 XR_949828 NM_001161452 NP_001154924 NM_001161454 NP_001154926 NM_001300763 NP_001287692 NM_153611 NP_705839
|
| Function |
Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Late endosome membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Lysosome membrane {ECO:0000269|PubMed:17897319}; Multi-pass membrane protein {ECO:0000269|PubMed:17897319}.
|
![Western Blot: Cytochrome B, Ascorbate Dependent 3 Antibody [NBP2-30527] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10Lane 2: Negative control (vector only transfected HEK293T lysate)Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY407026)](http://www.bioprodhub.com/system/product_images/ab_products/5/sub_8/26759_Cytochrome%2520B-%2520Ascorbate%2520Dependent%25203%2520Antibody-Western%2520Blot-NBP2-30527-img0002.jpg)
