| Gene Symbol | Pla2g4a |
|---|---|
| Entrez Gene | 18783 |
| Alt Symbol | Pla2g4, cPLA2, cPLA2-alpha, cPLA2alpha |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| Other Description | Cytosolic phospholipase A2 (CPLA2)|Type IV PLA2|cytosolic PLA2|cytosolic phospholipase A2|phospholipase A2 group IVA|phospholipase A2, group 4 |
| Swissprots | P47713 |
| Accessions | EDL39489 P47713 AK004701 BAB23486 AK144750 BAE26047 AK172121 BC003816 AAH03816 BQ033204 M72394 AAB00796 XM_006529252 XP_006529315 NM_001305632 NP_001292561 NM_008869 NP_032895 |
| Function | Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response. |
| Subcellular Location | Cytoplasm. Cytoplasmic vesicle. Note=Translocates to membrane vesicles in a calcium-dependent fashion. |
| Top Pathways | Glutamatergic synapse, Choline metabolism in cancer, Oxytocin signaling pathway, Inflammatory mediator regulation of TRP channels, VEGF signaling pathway |