| Gene Symbol |
ZNF260
|
| Entrez Gene |
339324
|
| Alt Symbol |
OZRF1, PEX1, ZFP260
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger protein 260
|
| Other Description |
zfp-260
|
| Swissprots |
Q0VF43 Q3ZCT1
|
| Accessions |
Q3ZCT1 AK122854 AK123830 AK291442 BAF84131 BC042676 AAH42676 BC119003 AAI19004 BC122549 AAI22550 BI493993 BQ938102 DB283305 XM_011526897 XP_011525199 NM_001012756 NP_001012774 NM_001166036 NP_001159508 NM_001166037 NP_001159509 NM_001166038 NP_001159510
|
| Function |
Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA. Also acts as a cofactor with GATA4, a key cardiac regulator (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:16166646}.
|