| Gene Symbol |
EFHC1
|
| Entrez Gene |
114327
|
| Alt Symbol |
EJM1, dJ304B14.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
EF-hand domain (C-terminal) containing 1
|
| Other Description |
EF-hand domain-containing protein 1|myoclonin-1
|
| Swissprots |
Q6E1U8 Q6E1U7 F5GZD8 Q5XKM4 Q9NVW6 Q5JVL4 B4DMU3 Q8WUL2
|
| Accessions |
CAJ42791 EAX04370 EAX04371 EAX04372 Q5JVL4 AK001328 BAA91628 AK094609 AK225543 AK295064 BAH11960 AK297632 BAG60005 AL122084 AY608689 AAT67418 AY608690 AAT67419 BC012921 BC020210 AAH20210 BQ268404 BQ270560 DA906669 DQ892170 ABM83096 DQ895364 ABM86290 EU520261 ACB20691 NM_001172420 NP_001165891 NM_018100 NP_060570 NR_033327
|
| Function |
Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration (PubMed:22926142). May enhance calcium influx through CACNA1E and stimulate programmed cell death (PubMed:15258581). {ECO:0000269|PubMed:15258581, ECO:0000269|PubMed:22926142}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:22926142}.
|
| Tissue Specificity |
Widely expressed. Not detected in lymphocytes. {ECO:0000269|PubMed:15258581}.
|
![Western Blot: EFHC1 Overexpression Lysate (Adult Normal) [NBL1-10139] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for EFHC1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8855_EFHC1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10139-img0002.jpg)