Gene Symbol | UNC5CL |
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Entrez Gene | 222643 |
Alt Symbol | MUXA, ZUD |
Species | Human |
Gene Type | protein-coding |
Description | unc-5 homolog C (C. elegans)-like |
Other Description | UNC5C-like protein|ZU5 and death domain containing|protein unc-5 homolog C-like |
Swissprots | Q8IV45 Q5TGU1 |
Accessions | EAX04007 Q8IV45 AI791395 AY510109 AAS80165 BC035284 AAH35284 BM312066 JF681947 AEB96256 NM_173561 NP_775832 |
Function | Inhibits NF-kappa-B-dependent transcription by impairing NF-kappa-B binding to its targets. {ECO:0000269|PubMed:14769797}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:14769797}. |
Tissue Specificity | Expressed in pancreas, liver and kidney. {ECO:0000269|PubMed:14769797}. |
ZUD CRISPR/Cas9 KO Plasmid (h) - sc-415160 from Santa Cruz Biotechnology
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ZUD HDR Plasmid (h) - sc-415160-HDR from Santa Cruz Biotechnology
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ZUD Double Nickase Plasmid (h) - sc-415160-NIC from Santa Cruz Biotechnology
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ZUD Double Nickase Plasmid (h2) - sc-415160-NIC-2 from Santa Cruz Biotechnology
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ZUD CRISPR Activation Plasmid (h) - sc-415160-ACT from Santa Cruz Biotechnology
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ZUD CRISPR Activation Plasmid (h2) - sc-415160-ACT-2 from Santa Cruz Biotechnology
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ZUD Lentiviral Activation Particles (h) - sc-415160-LAC from Santa Cruz Biotechnology
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ZUD Lentiviral Activation Particles (h2) - sc-415160-LAC-2 from Santa Cruz Biotechnology
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ZUD siRNA (h) - sc-95528 from Santa Cruz Biotechnology
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ZUD shRNA Plasmid (h) - sc-95528-SH from Santa Cruz Biotechnology
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ZUD shRNA (h) Lentiviral Particles - sc-95528-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU119781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22503 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22503 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08879 from Sigma-Aldrich
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UNC5CL siRNA (Human) - CRJ6574 from Cohesion Biosciences
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UNC5CL - MBS8208370 from MyBioSource
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shRNA set against Human UNC5CL (NM_173561.2) - SHH440597 from Creative biogene
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UNC5CL shRNA Plasmid (Human) - CHJ6574 from Cohesion Biosciences
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UNC5CL miRNA 3'UTR clone - MiUTR3H-16506 from Creative biogene
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