| Gene Symbol |
NOX3
|
| Entrez Gene |
50508
|
| Alt Symbol |
GP91-3, MOX-2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NADPH oxidase 3
|
| Other Description |
NADPH oxidase catalytic subunit-like 3|gp91phox homolog 3|mitogenic oxidase 2
|
| Swissprots |
Q9HBJ9 Q9HBY0
|
| Accessions |
CAP47045 EAW47689 Q9HBY0 AF190122 AAG17121 AF229177 AAG15435 BC160172 AAI60172 NM_015718 NP_056533
|
| Function |
NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. {ECO:0000269|PubMed:15824103}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Top Pathways |
Leukocyte transendothelial migration, Phagosome, Osteoclast differentiation
|
![Western Blot: NOX3 Overexpression Lysate (Adult Normal) [NBP2-07120] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NOX3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9940_NOX3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07120-img0001.jpg)