Gene Symbol |
RGR
|
Entrez Gene |
5995
|
Alt Symbol |
RP44
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
retinal G protein coupled receptor
|
Other Description |
RGR-opsin|RPE retinal G-protein coupled receptor|RPE-retinal G protein-coupled receptor
|
Swissprots |
Q96FC5 P47804 A6NKK7
|
Accessions |
AAB92384 EAW80354 EAW80355 EAW80356 EAW80357 EAW80358 P47804 BC008094 AAH08094 BC011349 AAH11349 BC027987 BC042536 BG912392 BX641033 DQ892074 ABM83000 DQ895267 ABM86193 DQ980610 U14910 AAA56748 XM_011540028 XP_011538330 NM_001012720 NP_001012738 NM_001012722 NP_001012740 NM_002921 NP_002912
|
Function |
Receptor for all-trans- and 11-cis-retinal. Binds preferentially to the former and may catalyze the isomerization of the chromophore by a retinochrome-like mechanism.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Preferentially expressed at high levels in the retinal pigment epithelium (RPE) and Mueller cells of the neural retina.
|