| Gene Symbol | ACOX2 |
|---|---|
| Entrez Gene | 8309 |
| Alt Symbol | BCOX, BRCACOX, BRCOX, THCCox |
| Species | Human |
| Gene Type | protein-coding |
| Description | acyl-CoA oxidase 2, branched chain |
| Other Description | 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase|THCA-CoA oxidase|acyl-Coenzyme A oxidase 2, branched chain|peroxisomal acyl-coenzyme A oxidase 2|peroxisomal branched chain acyl-CoA oxidase|trihydroxycoprostanoyl-CoA oxidase |
| Swissprots | A6NF16 Q99424 B2R8U5 |
| Accessions | CAB65596 CBF60593 CBF65743 CBF73142 CBU85833 CBU90614 CBU96030 EAW65375 EAW65376 EAW65377 Q99424 AK298402 BAG60633 AK313512 BAG36292 BC033517 BC047700 AAH47700 BG698950 BI490007 X95190 CAA64489 XM_005265505 XP_005265562 XM_005265506 XP_005265563 XM_006713340 XP_006713403 XM_011534147 XP_011532449 XM_011534148 XP_011532450 NM_003500 NP_003491 |
| Function | Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids. |
| Subcellular Location | Peroxisome. |
| Tissue Specificity | Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney. |
| Top Pathways | Primary bile acid biosynthesis, PPAR signaling pathway, Peroxisome |