Gene Symbol | ACOX2 |
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Entrez Gene | 8309 |
Alt Symbol | BCOX, BRCACOX, BRCOX, THCCox |
Species | Human |
Gene Type | protein-coding |
Description | acyl-CoA oxidase 2, branched chain |
Other Description | 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase|THCA-CoA oxidase|acyl-Coenzyme A oxidase 2, branched chain|peroxisomal acyl-coenzyme A oxidase 2|peroxisomal branched chain acyl-CoA oxidase|trihydroxycoprostanoyl-CoA oxidase |
Swissprots | A6NF16 Q99424 B2R8U5 |
Accessions | CAB65596 CBF60593 CBF65743 CBF73142 CBU85833 CBU90614 CBU96030 EAW65375 EAW65376 EAW65377 Q99424 AK298402 BAG60633 AK313512 BAG36292 BC033517 BC047700 AAH47700 BG698950 BI490007 X95190 CAA64489 XM_005265505 XP_005265562 XM_005265506 XP_005265563 XM_006713340 XP_006713403 XM_011534147 XP_011532449 XM_011534148 XP_011532450 NM_003500 NP_003491 |
Function | Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids. |
Subcellular Location | Peroxisome. |
Tissue Specificity | Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney. |
Top Pathways | Primary bile acid biosynthesis, PPAR signaling pathway, Peroxisome |
ACOX2 CRISPR/Cas9 KO Plasmid (h) - sc-408787 from Santa Cruz Biotechnology
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ACOX2 HDR Plasmid (h) - sc-408787-HDR from Santa Cruz Biotechnology
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ACOX2 Double Nickase Plasmid (h) - sc-408787-NIC from Santa Cruz Biotechnology
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ACOX2 Double Nickase Plasmid (h2) - sc-408787-NIC-2 from Santa Cruz Biotechnology
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ACOX2 CRISPR Activation Plasmid (h) - sc-408787-ACT from Santa Cruz Biotechnology
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ACOX2 CRISPR Activation Plasmid (h2) - sc-408787-ACT-2 from Santa Cruz Biotechnology
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ACOX2 Lentiviral Activation Particles (h) - sc-408787-LAC from Santa Cruz Biotechnology
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ACOX2 Lentiviral Activation Particles (h2) - sc-408787-LAC-2 from Santa Cruz Biotechnology
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ACOX2 siRNA (h) - sc-78421 from Santa Cruz Biotechnology
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ACOX2 shRNA Plasmid (h) - sc-78421-SH from Santa Cruz Biotechnology
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ACOX2 shRNA (h) Lentiviral Particles - sc-78421-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU041521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2734 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2734 from Sigma-Aldrich
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ACOX2 siRNA (Human) - CRH5434 from Cohesion Biosciences
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ACOX2 RNAi - H00008309-R01 from Novus Biologicals
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ACOX2 - MBS8204638 from MyBioSource
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shRNA set against Human ACOX2 (NM_003500.3) - SHH230516 from Creative biogene
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Human ACOX2 siRNA - orb265936 from Biorbyt
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ACOX2 shRNA Plasmid (Human) - CHH5434 from Cohesion Biosciences
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ACOX2 miRNA 3'UTR clone - MiUTR3H-04278 from Creative biogene
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