Gene Symbol | BGLAP |
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Entrez Gene | 632 |
Alt Symbol | BGP, OC, OCN |
Species | Human |
Gene Type | protein-coding |
Description | bone gamma-carboxyglutamate (gla) protein |
Other Description | bone Gla protein|bone gamma-carboxyglutamate (gla) protein (osteocalcin)|gamma-carboxyglutamic acid-containing protein|osteocalcin |
Swissprots | P02818 Q5TCK6 |
Accessions | AAF05868 AAY16981 CAA27763 CAI61690 CAJ42738 CBW53724 CBX74359 EAW52986 P02818 BC113432 AAI13433 BC113434 AAI13435 BU622466 CA428336 HQ258037 ADR82791 X51699 CAA35996 X53698 CAA37736 NM_199173 NP_954642 |
Function | Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. |
Subcellular Location | Secreted. |
osteocalcin CRISPR/Cas9 KO Plasmid (h) - sc-400299 from Santa Cruz Biotechnology
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osteocalcin HDR Plasmid (h) - sc-400299-HDR from Santa Cruz Biotechnology
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osteocalcin Double Nickase Plasmid (h) - sc-400299-NIC from Santa Cruz Biotechnology
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osteocalcin Double Nickase Plasmid (h2) - sc-400299-NIC-2 from Santa Cruz Biotechnology
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osteocalcin CRISPR Activation Plasmid (h) - sc-400299-ACT from Santa Cruz Biotechnology
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osteocalcin CRISPR Activation Plasmid (h2) - sc-400299-ACT-2 from Santa Cruz Biotechnology
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osteocalcin Lentiviral Activation Particles (h) - sc-400299-LAC from Santa Cruz Biotechnology
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osteocalcin Lentiviral Activation Particles (h2) - sc-400299-LAC-2 from Santa Cruz Biotechnology
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osteocalcin siRNA (h) - sc-40790 from Santa Cruz Biotechnology
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osteocalcin shRNA Plasmid (h) - sc-40790-SH from Santa Cruz Biotechnology
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osteocalcin shRNA (h) Lentiviral Particles - sc-40790-V from Santa Cruz Biotechnology
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Osteocalcin RNAi - H00000632-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN3962 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3962 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00058 from Sigma-Aldrich
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BGLAP siRNA (Human) - CRH0428 from Cohesion Biosciences
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BGLAP - MBS8201573 from MyBioSource
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osteocalcin CRISPR/Cas9 KO Plasmid (h2) - sc-400299-KO-2 from Santa Cruz Biotechnology
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osteocalcin HDR Plasmid (h2) - sc-400299-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human BGLAP (NM_199173.4) - SHH246514 from Creative biogene
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Human BGLAP siRNA - orb260930 from Biorbyt
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BGLAP shRNA Plasmid (Human) - CHH0428 from Cohesion Biosciences
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BGLAP miRNA 3'UTR clone - MiUTR3H-00273 from Creative biogene
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