Gene Symbol | MAP3K6 |
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Entrez Gene | 9064 |
Alt Symbol | ASK2, MAPKKK6, MEKK6 |
Species | Human |
Gene Type | protein-coding |
Description | mitogen-activated protein kinase kinase kinase 6 |
Other Description | apoptosis signal-regulating kinase 2 |
Swissprots | Q96B75 Q59HF4 Q75PK3 A2VDG5 O95382 Q5SSD4 A2ACE8 A2VDG4 |
Accessions | CCQ43272 EAX07758 JE0363 O95382 AB167411 BAD12485 AB208805 BAD92042 AF100318 AAD05304 AI582755 AI658745 AW771625 BC015914 AAH15914 BC109032 AAI09033 BC129950 AAI29951 BC129951 AAI29952 BC169211 BF115137 XM_011542406 XP_011540708 XR_241205 XR_946794 XR_946795 NM_001297609 NP_001284538 NM_004672 NP_004663 |
Function | Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways. {ECO:0000269|PubMed:17210579, ECO:0000269|PubMed:9875215}. |
Top Pathways | MAPK signaling pathway |
MAP3K6 CRISPR/Cas9 KO Plasmid (h) - sc-407051 from Santa Cruz Biotechnology
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MAP3K6 HDR Plasmid (h) - sc-407051-HDR from Santa Cruz Biotechnology
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MAP3K6 Double Nickase Plasmid (h) - sc-407051-NIC from Santa Cruz Biotechnology
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MAP3K6 Double Nickase Plasmid (h2) - sc-407051-NIC-2 from Santa Cruz Biotechnology
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MAP3K6 CRISPR Activation Plasmid (h) - sc-407051-ACT from Santa Cruz Biotechnology
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MAP3K6 CRISPR Activation Plasmid (h2) - sc-407051-ACT-2 from Santa Cruz Biotechnology
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MAP3K6 Lentiviral Activation Particles (h) - sc-407051-LAC from Santa Cruz Biotechnology
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MAP3K6 Lentiviral Activation Particles (h2) - sc-407051-LAC-2 from Santa Cruz Biotechnology
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MAP3K6 siRNA (h) - sc-62598 from Santa Cruz Biotechnology
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MAP3K6 shRNA Plasmid (h) - sc-62598-SH from Santa Cruz Biotechnology
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MAP3K6 shRNA (h) Lentiviral Particles - sc-62598-V from Santa Cruz Biotechnology
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MAP3K6 RNAi - H00009064-R02 from Novus Biologicals
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MISSION® esiRNA - EHU119351 from Sigma-Aldrich
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MISSION® siRNA - SIHK1153 from Sigma-Aldrich
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MISSION® siRNA - SIHK1155 from Sigma-Aldrich
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MISSION® siRNA - SIHK1154 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12994 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12994 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00469 from Sigma-Aldrich
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MAP3K6 siRNA (Human) - CRH5983 from Cohesion Biosciences
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shRNA set against Human MAP3K6 (NM_004672.3) - SHH337731 from Creative biogene
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MAP3K6 shRNA Plasmid (Human) - CHH5983 from Cohesion Biosciences
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MAP3K6 miRNA 3'UTR clone - MiUTR1H-06065 from Creative biogene
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