| Gene Symbol |
TDRD7
|
| Entrez Gene |
23424
|
| Alt Symbol |
CATC4, PCTAIRE2BP, TRAP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tudor domain containing 7
|
| Other Description |
PCTAIRE2-binding protein|tudor domain-containing protein 7|tudor repeat associator with PCTAIRE 2
|
| Swissprots |
Q96JT1 E7EQD4 Q8NHU6 Q5VV27 B4DG99 Q9UFF0 A6NCI6 B2RBX3 Q9Y2M3 B4DXF7
|
| Accessions |
EAW58843 EAW58844 Q8NHU6 AB025254 BAA76379 AK294488 BAG57710 AK301954 BAG63369 AK310227 AK314853 BAG37370 AL122110 CAB59271 AW268820 BC028694 AAH28694 DB455041 DQ894121 ABM85047 XM_006717026 XP_006717089 XM_011518424 XP_011516726 XR_929741 NM_001302884 NP_001289813 NM_014290 NP_055105
|
| Function |
Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis. {ECO:0000269|PubMed:21436445}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:21436445}. Note=Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By similarity). {ECO:0000250}.
|