Gene Symbol | FCRL2 |
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Entrez Gene | 79368 |
Alt Symbol | CD307b, FCRH2, IFGP4, IRTA4, SPAP1, SPAP1A, SPAP1B, SPAP1C |
Species | Human |
Gene Type | protein-coding |
Description | Fc receptor-like 2 |
Other Description | Fc receptor-like protein 2|IFGP family protein 4|SH2 domain containing phosphatase anchor protein 1|fc receptor homolog 2|immune receptor translocation-associated protein 4|immunoglobulin receptor translocation-associated protein 4|immunoglobulin superfamily Fc receptor, gp42 |
Swissprots | Q9BZI4 A6NMS0 A1L307 Q6NTA1 Q9BZI6 Q96LA5 A0N0M5 Q9BZI5 |
Accessions | ABK41916 EAW52864 EAW52865 EAW52866 EAW52867 EAW52868 EAW52869 Q96LA5 AF319438 AAK01402 AF319439 AAK01403 AF319440 AAK01404 AF390037 AAM12152 AF459633 AAL60249 AK301113 BAG62711 AK303549 BAG64574 AL833194 AL833361 AY043465 AAK91778 AY358130 AAQ88497 BC069185 AAH69185 BC129836 AAI29837 XM_006711535 XP_006711598 XM_011509974 XP_011508276 XM_011509975 XP_011508277 XM_011509976 XP_011508278 XM_011509977 XP_011508279 XM_011509978 XP_011508280 XM_011509979 XP_011508281 XM_011509980 XP_011508282 NM_001159488 NP_001152960 NM_030764 NP_110391 NR_125358 NM_138738 |
Function | May have an regulatory role in normal and neoplastic B cell development. {ECO:0000269|PubMed:11493702}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:16849395}; Single-pass type I membrane protein {ECO:0000269|PubMed:16849395}. |
Tissue Specificity | Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B- cell lines. Preferentially expressed in memory B-cells (at protein level). {ECO:0000269|PubMed:11162587, ECO:0000269|PubMed:11493702, ECO:0000269|PubMed:11929751, ECO:0000269|PubMed:16849395}. |
FcRH2 CRISPR/Cas9 KO Plasmid (h) - sc-413163 from Santa Cruz Biotechnology
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FcRH2 HDR Plasmid (h) - sc-413163-HDR from Santa Cruz Biotechnology
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FcRH2 Double Nickase Plasmid (h) - sc-413163-NIC from Santa Cruz Biotechnology
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FcRH2 Double Nickase Plasmid (h2) - sc-413163-NIC-2 from Santa Cruz Biotechnology
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FcRH2 CRISPR Activation Plasmid (h) - sc-413163-ACT from Santa Cruz Biotechnology
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FcRH2 CRISPR Activation Plasmid (h2) - sc-413163-ACT-2 from Santa Cruz Biotechnology
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FcRH2 Lentiviral Activation Particles (h) - sc-413163-LAC from Santa Cruz Biotechnology
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FcRH2 Lentiviral Activation Particles (h2) - sc-413163-LAC-2 from Santa Cruz Biotechnology
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FcRH2 siRNA (h) - sc-45686 from Santa Cruz Biotechnology
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FcRH2 shRNA Plasmid (h) - sc-45686-SH from Santa Cruz Biotechnology
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FcRH2 shRNA (h) Lentiviral Particles - sc-45686-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU066541 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8602 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8602 from Sigma-Aldrich
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FCRL2 siRNA (Human) - CRJ2375 from Cohesion Biosciences
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FCRL2/FcRH2 RNAi - H00079368-R04 from Novus Biologicals
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FCRL2 - MBS829347 from MyBioSource
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shRNA set against Human FCRL2 (NM_030764.3) - SHH293861 from Creative biogene
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Human FCRL2 siRNA - orb272876 from Biorbyt
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FCRL2 shRNA Plasmid (Human) - CHJ2375 from Cohesion Biosciences
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FCRL2 miRNA 3'UTR clone - MiUTR4H-TG03506 from Creative biogene
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