Gene Symbol |
SRPRB
|
Entrez Gene |
58477
|
Alt Symbol |
APMCF1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
signal recognition particle receptor, B subunit
|
Other Description |
SR-beta|signal recognition particle receptor subunit beta|signal recognition particle receptor, beta subunit
|
Swissprots |
Q8N2D8 Q9Y5M8 Q6P595
|
Accessions |
CAC39810 CAI72181 EAW79160 EAW79161 EAW79162 Q9Y5M8 AF086914 AAP97144 AF141882 AAD34888 AK027307 AK027525 BAB55176 AK075531 BAC11675 BC019005 BC063001 AAH63001 BC065299 AAH65299 DB448771 DQ601932 HQ448094 ADQ32575 NM_021203 NP_067026
|
Function |
Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR (By similarity). {ECO:0000250}.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
|
Top Pathways |
Protein export
|