Gene Symbol | TCEB3C |
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Entrez Gene | 162699 |
Alt Symbol | HsT829, TCEB3L2 |
Species | Human |
Gene Type | protein-coding |
Description | transcription elongation factor B polypeptide 3C (elongin A3) |
Other Description | RNA polymerase II transcription factor SIII subunit A3|eloA3|elongin-A3 |
Swissprots | Q8NG57 |
Accessions | Q8NG57 AB076840 BAC01113 BC172326 AAI72326 BQ185879 EU446606 ABZ92135 NM_145653 NP_663628 |
Function | SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A3 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). {ECO:0000269|PubMed:11994304}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Widely expressed. |
Elongin A3 CRISPR/Cas9 KO Plasmid (h) - sc-418260 from Santa Cruz Biotechnology
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Elongin A3 HDR Plasmid (h) - sc-418260-HDR from Santa Cruz Biotechnology
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Elongin A3 Double Nickase Plasmid (h) - sc-418260-NIC from Santa Cruz Biotechnology
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Elongin A3 Double Nickase Plasmid (h2) - sc-418260-NIC-2 from Santa Cruz Biotechnology
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Elongin A3 CRISPR Activation Plasmid (h) - sc-418260-ACT from Santa Cruz Biotechnology
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Elongin A3 CRISPR Activation Plasmid (h2) - sc-418260-ACT-2 from Santa Cruz Biotechnology
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Elongin A3 Lentiviral Activation Particles (h) - sc-418260-LAC from Santa Cruz Biotechnology
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Elongin A3 Lentiviral Activation Particles (h2) - sc-418260-LAC-2 from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU148171 from Sigma-Aldrich
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MISSION® esiRNA - EHU148941 from Sigma-Aldrich
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MISSION® siRNA - SIHK2249 from Sigma-Aldrich
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MISSION® siRNA - SIHK2251 from Sigma-Aldrich
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MISSION® siRNA - SIHK2250 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2540 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2540 from Sigma-Aldrich
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TCEB3C siRNA (Human) - CRJ5959 from Cohesion Biosciences
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TCEB3C - MBS8228417 from MyBioSource
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Elongin A3 CRISPR/Cas9 KO Plasmid (h2) - sc-418260-KO-2 from Santa Cruz Biotechnology
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Elongin A3 HDR Plasmid (h2) - sc-418260-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human TCEB3C (NM_145653.3) - SHH424708 from Creative biogene
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TCEB3C shRNA Plasmid (Human) - CHJ5959 from Cohesion Biosciences
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TCEB3C miRNA 3'UTR clone - MiUTR1H-10264 from Creative biogene
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