Gene Symbol | IGFBP7 |
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Entrez Gene | 3490 |
Alt Symbol | AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF |
Species | Human |
Gene Type | protein-coding |
Description | insulin-like growth factor binding protein 7 |
Other Description | IGF-binding protein 7|IGFBP-rP1|PGI2-stimulating factor|angiomodulin|insulin-like growth factor-binding protein 7|prostacyclin-stimulating factor|tumor-derived adhesion factor |
Swissprots | B4E1N2 Q53YE6 B7Z9W7 Q9UCA8 Q07822 Q16270 |
Accessions | AAR89912 CAJ21555 EAX05520 EAX05521 Q16270 AF540057 AAN23122 AI761388 AK303915 BAG64844 AK316082 BAH14453 BC017201 AAH17201 BC066339 AAH66339 BT006654 AAP35300 L19182 AAA16187 S75725 AAB32370 NM_001253835 NP_001240764 NM_001553 NP_001544 |
Function | Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. {ECO:0000269|PubMed:8117260, ECO:0000269|PubMed:8939990}. |
Subcellular Location | Secreted. |
IGFBP7 CRISPR/Cas9 KO Plasmid (h) - sc-418272 from Santa Cruz Biotechnology
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IGFBP7 HDR Plasmid (h) - sc-418272-HDR from Santa Cruz Biotechnology
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IGFBP7 Double Nickase Plasmid (h) - sc-418272-NIC from Santa Cruz Biotechnology
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IGFBP7 Double Nickase Plasmid (h2) - sc-418272-NIC-2 from Santa Cruz Biotechnology
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IGFBP7 CRISPR Activation Plasmid (h) - sc-418272-ACT from Santa Cruz Biotechnology
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IGFBP7 CRISPR Activation Plasmid (h2) - sc-418272-ACT-2 from Santa Cruz Biotechnology
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IGFBP7 Lentiviral Activation Particles (h) - sc-418272-LAC from Santa Cruz Biotechnology
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IGFBP7 Lentiviral Activation Particles (h2) - sc-418272-LAC-2 from Santa Cruz Biotechnology
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IGFBP7 siRNA (h) - sc-39593 from Santa Cruz Biotechnology
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IGFBP7 shRNA Plasmid (h) - sc-39593-SH from Santa Cruz Biotechnology
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IGFBP7 shRNA (h) Lentiviral Particles - sc-39593-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU039721 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10526 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10526 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01982 from Sigma-Aldrich
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IGFBP7 siRNA (Human) - CRH2361 from Cohesion Biosciences
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IGFBP7 - MBS8236937 from MyBioSource
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shRNA set against Human IGFBP7 (NM_001553.2) - SHH317601 from Creative biogene
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Human IGFBP7 siRNA - orb262863 from Biorbyt
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IGFBP7 shRNA Plasmid (Human) - CHH2361 from Cohesion Biosciences
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IGFBP7 miRNA 3'UTR clone - MiUTR3H-05368 from Creative biogene
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