Gene Symbol | HSF4 |
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Entrez Gene | 3299 |
Alt Symbol | CTM, CTRCT5 |
Species | Human |
Gene Type | protein-coding |
Description | heat shock transcription factor 4 |
Other Description | HSF 4|HSTF 4|hHSF4|heat shock factor protein 4 |
Swissprots | Q9ULV6 Q99472 Q9ULV5 |
Accessions | BAA84581 EAW83083 EAW83084 EAW83085 EAW83086 Q9ULV5 AB029348 BAA84582 AK225152 AK293631 BAG57087 AK296210 BAG58936 AK307211 AK308638 BC130383 BC146446 AAI46447 BC153061 AAI53062 BG980713 BI001524 BM768246 BM805441 BX348481 CA412687 D87673 BAA13433 DA111974 DA372008 NM_001040667 NP_001035757 NM_001538 NP_001529 |
Function | DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription. {ECO:0000269|PubMed:16371476}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Expressed in heart, skeletal muscle, eye and brain, and at much lower levels in some other tissues. {ECO:0000269|PubMed:12089525}. |
HSF4 CRISPR/Cas9 KO Plasmid (h) - sc-403850 from Santa Cruz Biotechnology
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HSF4 HDR Plasmid (h) - sc-403850-HDR from Santa Cruz Biotechnology
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HSF4 Double Nickase Plasmid (h) - sc-403850-NIC from Santa Cruz Biotechnology
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HSF4 Double Nickase Plasmid (h2) - sc-403850-NIC-2 from Santa Cruz Biotechnology
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HSF4 CRISPR Activation Plasmid (h) - sc-403850-ACT from Santa Cruz Biotechnology
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HSF4 CRISPR Activation Plasmid (h2) - sc-403850-ACT-2 from Santa Cruz Biotechnology
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HSF4 Lentiviral Activation Particles (h) - sc-403850-LAC from Santa Cruz Biotechnology
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HSF4 Lentiviral Activation Particles (h2) - sc-403850-LAC-2 from Santa Cruz Biotechnology
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HSF4 siRNA (h) - sc-37924 from Santa Cruz Biotechnology
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HSF4 shRNA Plasmid (h) - sc-37924-SH from Santa Cruz Biotechnology
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HSF4 shRNA (h) Lentiviral Particles - sc-37924-V from Santa Cruz Biotechnology
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HSF4 RNAi - H00003299-R01 from Novus Biologicals
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MISSION® esiRNA - EHU144091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10341 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00378 from Sigma-Aldrich
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HSF4 siRNA (Human) - CRH2255 from Cohesion Biosciences
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HSF4 - MBS8241209 from MyBioSource
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shRNA set against Human HSF4 (NM_001538.3) - SHH315405 from Creative biogene
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HSF4 shRNA Plasmid (Human) - CHH2255 from Cohesion Biosciences
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HSF4 miRNA 3'UTR clone - MiUTR3H-04989 from Creative biogene
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HSF4 miRNA 3'UTR clone - MiUTR3H-04990 from Creative biogene
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