Gene Symbol | ARL6IP4 |
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Entrez Gene | 51329 |
Alt Symbol | SFRS20, SR-25, SRp25, SRrp37 |
Species | Human |
Gene Type | protein-coding |
Description | ADP-ribosylation factor-like 6 interacting protein 4 |
Other Description | ADP-ribosylation factor-like protein 6-interacting protein 4|ADP-ribosylation-like factor 6 interacting protein 4|ARL-6-interacting protein 4|HSP-975|HSVI binding protein|HSVI-binding protein|SR-15|SRp25 nuclear protein|aip-4|splicing factor SRrp37|splicing factor, arginine/serine-rich 20|splicing regulator SRrp38 |
Swissprots | B3V0L1 B3V0L0 Q9NR05 A4UCR8 Q504R8 Q96BI2 Q4F966 Q66PJ3 Q9P2R9 |
Accessions | EAW98373 EAW98374 EAW98375 EAW98376 EAW98377 EAW98378 EAW98379 EAW98380 EAW98381 EAW98382 Q66PJ3 AA887283 AB035384 BAA94744 AF267748 AAF76892 AK027285 AK315759 BAG38112 AW189362 BC001958 AAH01958 BC015569 AAH15569 BC015909 AAH15909 BC094839 AAH94839 BQ643520 CD672894 DQ099385 AAZ13761 EF036485 ABO65071 EU624490 ACF07995 EU624491 ACF07996 NM_001002251 NP_001002251 NM_001002252 NP_001002252 NM_001278378 NP_001265307 NM_001278379 NP_001265308 NM_001278380 NP_001265309 NM_016638 NP_057722 NM_018694 NP_061164 NR_103512 |
Function | Involved in modulating alternative pre-mRNA splicing with either 5' distal site activation or preferential use of 3' proximal site. In case of infection by Herpes simplex virus (HSVI), may act as a splicing inhibitor of HSVI pre-mRNA. {ECO:0000269|PubMed:19582790}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:19582790}. Nucleus speckle {ECO:0000269|PubMed:19582790}. |
Tissue Specificity | Isoforms 3 and 7 were identified in brain, pancreas, prostate, and testis, but little or no message could be detected in other tissues. {ECO:0000269|PubMed:19582790}. |
ARL6IP4 CRISPR/Cas9 KO Plasmid (h) - sc-412185 from Santa Cruz Biotechnology
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ARL6IP4 HDR Plasmid (h) - sc-412185-HDR from Santa Cruz Biotechnology
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ARL6IP4 Double Nickase Plasmid (h) - sc-412185-NIC from Santa Cruz Biotechnology
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ARL6IP4 Double Nickase Plasmid (h2) - sc-412185-NIC-2 from Santa Cruz Biotechnology
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ARL6IP4 CRISPR Activation Plasmid (h) - sc-412185-ACT from Santa Cruz Biotechnology
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ARL6IP4 CRISPR Activation Plasmid (h2) - sc-412185-ACT-2 from Santa Cruz Biotechnology
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ARL6IP4 Lentiviral Activation Particles (h) - sc-412185-LAC from Santa Cruz Biotechnology
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ARL6IP4 Lentiviral Activation Particles (h2) - sc-412185-LAC-2 from Santa Cruz Biotechnology
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ARL6IP4 siRNA (h) - sc-96185 from Santa Cruz Biotechnology
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ARL6IP4 shRNA Plasmid (h) - sc-96185-SH from Santa Cruz Biotechnology
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ARL6IP4 shRNA (h) Lentiviral Particles - sc-96185-V from Santa Cruz Biotechnology
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ARL6IP4 RNAi - H00051329-R01 from Novus Biologicals
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ARL6IP4 RNAi - H00051329-R04 from Novus Biologicals
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ARL6IP4 RNAi - H00051329-R03 from Novus Biologicals
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ARL6IP4 RNAi - H00051329-R02 from Novus Biologicals
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MISSION® esiRNA - EHU087871 from Sigma-Aldrich
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MISSION® esiRNA - EHU135261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3498 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3498 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02524 from Sigma-Aldrich
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ARL6IP4 siRNA (Human) - CRH9703 from Cohesion Biosciences
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ARL6IP4 - MBS8226078 from MyBioSource
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shRNA set against Human ARL6IP4 (NM_016638.2) - SHH240298 from Creative biogene
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shRNA set against Human ARL6IP4(NM_016638.2) - SHG073025 from Creative biogene
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shRNA set against Human ARL6IP4(NM_001002251.1) - SHG073043 from Creative biogene
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