Gene Symbol | PRKAR1B |
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Entrez Gene | 5575 |
Alt Symbol | PRKAR1 |
Species | Human |
Gene Type | protein-coding |
Description | protein kinase, cAMP-dependent, regulatory, type I, beta |
Other Description | cAMP-dependent protein kinase type I-beta regulatory subunit |
Swissprots | P31321 Q8N422 |
Accessions | EAW87163 EAW87164 EAW87165 EAW87166 P31321 AK098822 AK289464 BAF82153 AK297337 BAG59793 AK315951 BAH14322 AK315990 BAH14361 AL833563 BC013368 BC026734 AAH26734 BC036828 AAH36828 BC070478 AAH70478 CT003793 DA162030 DA210679 DA501689 DA910871 DC314672 EU832098 ACE87448 EU832191 ACE86761 M65066 AAC37564 XM_005249809 XP_005249866 XM_011515446 XP_011513748 XM_011515447 XP_011513749 NM_001164758 NP_001158230 NM_001164759 NP_001158231 NM_001164760 NP_001158232 NM_001164761 NP_001158233 NM_001164762 NP_001158234 NM_002735 NP_002726 |
Function | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. {ECO:0000269|PubMed:20819953}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:23115245}. |
Tissue Specificity | Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible. |
Top Pathways | Apoptosis, Insulin signaling pathway |
PKA Iβ reg siRNA (h) - sc-36238 from Santa Cruz Biotechnology
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PKA Iβ reg shRNA Plasmid (h) - sc-36238-SH from Santa Cruz Biotechnology
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PKA Iβ reg shRNA (h) Lentiviral Particles - sc-36238-V from Santa Cruz Biotechnology
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PKA regulatory subunit I beta RNAi - H00005575-R02 from Novus Biologicals
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PKA regulatory subunit I beta RNAi - H00005575-R01 from Novus Biologicals
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PKA regulatory subunit I beta RNAi - H00005575-R03 from Novus Biologicals
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MISSION® esiRNA - EHU057261 from Sigma-Aldrich
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MISSION® siRNA - SIHK1810 from Sigma-Aldrich
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MISSION® siRNA - SIHK1811 from Sigma-Aldrich
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MISSION® siRNA - SIHK1809 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17419 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17419 from Sigma-Aldrich
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PRKAR1B siRNA (Human) - CRH3745 from Cohesion Biosciences
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shRNA set against Human PRKAR1B (NM_002735.2) - SHH382744 from Creative biogene
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Human PRKAR1B siRNA - orb264247 from Biorbyt
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PRKAR1B shRNA Plasmid (Human) - CHH3745 from Cohesion Biosciences
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PRKAR1B miRNA 3'UTR clone - MiUTR3H-01907 from Creative biogene
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PRKAR1B miRNA 3'UTR clone - MiUTR3H-01908 from Creative biogene
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PRKAR1B miRNA 3'UTR clone - MiUTR3H-01909 from Creative biogene
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PRKAR1B miRNA 3'UTR clone - MiUTR3H-01910 from Creative biogene
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PRKAR1B miRNA 3'UTR clone - MiUTR3H-01911 from Creative biogene
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PRKAR1B miRNA 3'UTR clone - MiUTR3H-01912 from Creative biogene
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