Gene Symbol | LAMC1 |
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Entrez Gene | 3915 |
Alt Symbol | LAMB2 |
Species | Human |
Gene Type | protein-coding |
Description | laminin, gamma 1 (formerly LAMB2) |
Other Description | S-LAM gamma|S-laminin subunit gamma|laminin B2 chain|laminin subunit gamma-1|laminin-10 subunit gamma|laminin-11 subunit gamma|laminin-2 subunit gamma|laminin-3 subunit gamma|laminin-4 subunit gamma|laminin-6 subunit gamma|laminin-7 subunit gamma|laminin-8 subunit gamma|laminin-9 subunit gamma |
Swissprots | P11047 Q5VYE7 |
Accessions | AAA59492 EAW91144 EAW91145 P11047 BC015586 AAH15586 BC035429 BC067813 AAH67813 BF507385 BI768612 CF125114 CN388644 DA401791 J03202 AAA59488 M27654 AAA59489 X13939 CAA32122 NM_002293 NP_002284 |
Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. |
Tissue Specificity | Found in the basement membranes (major component). |
Top Pathways | Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Prion diseases, Amoebiasis |
Laminin γ-1 CRISPR/Cas9 KO Plasmid (h) - sc-401029 from Santa Cruz Biotechnology
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Laminin γ-1 HDR Plasmid (h) - sc-401029-HDR from Santa Cruz Biotechnology
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Laminin γ-1 Double Nickase Plasmid (h) - sc-401029-NIC from Santa Cruz Biotechnology
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Laminin γ-1 Double Nickase Plasmid (h2) - sc-401029-NIC-2 from Santa Cruz Biotechnology
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Laminin γ-1 CRISPR Activation Plasmid (h) - sc-401029-ACT from Santa Cruz Biotechnology
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Laminin γ-1 CRISPR Activation Plasmid (h2) - sc-401029-ACT-2 from Santa Cruz Biotechnology
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Laminin γ-1 Lentiviral Activation Particles (h) - sc-401029-LAC from Santa Cruz Biotechnology
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Laminin γ-1 Lentiviral Activation Particles (h2) - sc-401029-LAC-2 from Santa Cruz Biotechnology
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Laminin γ-1 siRNA (h) - sc-29388 from Santa Cruz Biotechnology
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Laminin γ-1 shRNA Plasmid (h) - sc-29388-SH from Santa Cruz Biotechnology
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Laminin γ-1 shRNA (h) Lentiviral Particles - sc-29388-V from Santa Cruz Biotechnology
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Laminin gamma 1 RNAi - H00003915-R01 from Novus Biologicals
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MISSION® esiRNA - EHU033431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11536 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11536 from Sigma-Aldrich
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LAMC1 siRNA (Human) - CRH2654 from Cohesion Biosciences
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shRNA set against Human LAMC1 (NM_002293.3) - SHH328299 from Creative biogene
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shRNA set against Human LAMC1(NM_002293.3) - SHH141641 from Creative biogene
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Human LAMC1 siRNA - orb263156 from Biorbyt
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LAMC1 shRNA Plasmid (Human) - CHH2654 from Cohesion Biosciences
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LAMC1 miRNA 3'UTR clone - MiUTR1H-05563 from Creative biogene
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