Gene Symbol | ZNHIT1 |
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Entrez Gene | 10467 |
Alt Symbol | CG1I, ZNFN4A1 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger, HIT-type containing 1 |
Other Description | H_DJ0747G18.14|cyclin-G1-binding protein 1|p18 Hamlet|p18Hamlet|putative cyclin G1 interacting protein|zinc finger HIT domain-containing protein 1|zinc finger protein subfamily 4A member 1|zinc finger protein, subfamily 4A (HIT domain containing), member 1|zinc finger, HIT domain containing 1|zinc finger, HIT type 1 |
Swissprots | Q6IB12 O43257 |
Accessions | AAD45833 EAW50206 EAW50207 EAW50208 EAW50209 O43257 AF093571 AAF03558 AK092478 AK125123 AK312136 BAG35072 BC001877 BC010454 BC017333 AAH17333 CR456992 CAG33273 DQ892275 ABM83201 DQ895476 ABM86402 U61837 AAB88578 XM_011515739 XP_011514041 NM_006349 NP_006340 |
Function | Seems to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity. {ECO:0000269|PubMed:17380123, ECO:0000269|PubMed:17892483}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17892483}. |
Tissue Specificity | Expressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine. {ECO:0000269|PubMed:17892483}. |
ZNHIT1 CRISPR/Cas9 KO Plasmid (h) - sc-408811 from Santa Cruz Biotechnology
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ZNHIT1 HDR Plasmid (h) - sc-408811-HDR from Santa Cruz Biotechnology
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ZNHIT1 Double Nickase Plasmid (h) - sc-408811-NIC from Santa Cruz Biotechnology
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ZNHIT1 Double Nickase Plasmid (h2) - sc-408811-NIC-2 from Santa Cruz Biotechnology
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ZNHIT1 CRISPR Activation Plasmid (h) - sc-408811-ACT from Santa Cruz Biotechnology
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ZNHIT1 CRISPR Activation Plasmid (h2) - sc-408811-ACT-2 from Santa Cruz Biotechnology
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ZNHIT1 Lentiviral Activation Particles (h) - sc-408811-LAC from Santa Cruz Biotechnology
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ZNHIT1 Lentiviral Activation Particles (h2) - sc-408811-LAC-2 from Santa Cruz Biotechnology
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ZNHIT1 siRNA (h) - sc-89847 from Santa Cruz Biotechnology
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ZNHIT1 shRNA Plasmid (h) - sc-89847-SH from Santa Cruz Biotechnology
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ZNHIT1 shRNA (h) Lentiviral Particles - sc-89847-V from Santa Cruz Biotechnology
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ZNHIT1 RNAi - H00010467-R01 from Novus Biologicals
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MISSION® esiRNA - EHU114611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23777 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23777 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00817 from Sigma-Aldrich
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ZNHIT1 siRNA (Human) - CRH7105 from Cohesion Biosciences
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ZNHIT1 - MBS8205437 from MyBioSource
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shRNA set against Human ZNHIT1 (NM_006349.2) - SHH455616 from Creative biogene
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ZNHIT1 shRNA Plasmid (Human) - CHH7105 from Cohesion Biosciences
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ZNHIT1 miRNA 3'UTR clone - MiUTR1H-11744 from Creative biogene
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