| Gene Symbol |
CBLL1
|
| Entrez Gene |
79872
|
| Alt Symbol |
HAKAI, RNF188
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
|
| Other Description |
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1|Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1|E-cadherin binding protein E7|E3 ubiquitin-protein ligase Hakai|RING finger protein 188|c-Cbl-like protein 1|casitas B-lineage lymphoma-transforming sequence-like protein 1
|
| Swissprots |
Q9H5S6 B7ZM03 Q75N03 Q8TAJ4
|
| Accessions |
AAS07390 CCQ43722 EAW83416 EAW83417 Q75N03 AI055864 AK026762 BAB15544 AK293352 BAG56868 AK307992 BC027460 AAH27460 BC130529 AAI30530 BC130531 AAI30532 BC144176 AAI44177 BP201841 BP280978 BX348716 CN274642 CN291556 DB033469 DB174309 HQ258273 ADR83027 XM_011516580 XP_011514882 NM_001284291 NP_001271220 NM_024814 NP_079090 NR_024199
|
| Function |
Promotes ubiquitination of several tyrosine- phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation (By similarity). {ECO:0000250}.
|
![Western Blot: CBLL1 Overexpression Lysate (Adult Normal) [NBP2-06280] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CBLL1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10604_CBLL1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06280-img0001.jpg)