| Gene Symbol | ADAM2 |
|---|---|
| Entrez Gene | 100009397 |
| Alt Symbol | - |
| Species | Rabbit |
| Gene Type | protein-coding |
| Description | ADAM metallopeptidase domain 2 |
| Other Description | ADAM 2|ADAM metallopeptidase domain 2 (fertilin beta)|PH-30|PH30|PH30-beta|disintegrin and metalloproteinase domain-containing protein 2|fertilin beta subunit|fertilin subunit beta |
| Swissprots | Q28660 |
| Accessions | Q28660 U46070 AAA93321 XM_008274019 XP_008272241 NM_001082677 NP_001076146 |
| Function | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity). {ECO:0000250}. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed specifically in testis. |