| Gene Symbol |
ADAM2
|
| Entrez Gene |
100009397
|
| Alt Symbol |
-
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
ADAM metallopeptidase domain 2
|
| Other Description |
ADAM 2|ADAM metallopeptidase domain 2 (fertilin beta)|PH-30|PH30|PH30-beta|disintegrin and metalloproteinase domain-containing protein 2|fertilin beta subunit|fertilin subunit beta
|
| Swissprots |
Q28660
|
| Accessions |
Q28660 U46070 AAA93321 XM_008274019 XP_008272241 NM_001082677 NP_001076146
|
| Function |
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Expressed specifically in testis.
|