| Gene Symbol | CXCR5 |
|---|---|
| Entrez Gene | 643 |
| Alt Symbol | BLR1, CD185, MDR15 |
| Species | Human |
| Gene Type | protein-coding |
| Description | chemokine (C-X-C motif) receptor 5 |
| Other Description | Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)|Burkitt lymphoma receptor 1, GTP-binding protein|C-X-C chemokine receptor type 5|CXC-R5|CXCR-5|MDR-15|monocyte-derived receptor 15 |
| Swissprots | Q14811 P32302 |
| Accessions | ABK41953 ACA05956 CAA58713 EAW67415 EAW67416 P32302 AK291512 BAF84201 AW575330 BC110352 AAI10353 CO958128 DA815880 X68149 CAA48252 X68829 CAA48723 NM_001716 NP_001707 NM_032966 NP_116743 |
| Function | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expression in mature B-cells and Burkitt lymphoma cells. |
| Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |