Gene Symbol | CXCR5 |
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Entrez Gene | 643 |
Alt Symbol | BLR1, CD185, MDR15 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-X-C motif) receptor 5 |
Other Description | Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)|Burkitt lymphoma receptor 1, GTP-binding protein|C-X-C chemokine receptor type 5|CXC-R5|CXCR-5|MDR-15|monocyte-derived receptor 15 |
Swissprots | Q14811 P32302 |
Accessions | ABK41953 ACA05956 CAA58713 EAW67415 EAW67416 P32302 AK291512 BAF84201 AW575330 BC110352 AAI10353 CO958128 DA815880 X68149 CAA48252 X68829 CAA48723 NM_001716 NP_001707 NM_032966 NP_116743 |
Function | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expression in mature B-cells and Burkitt lymphoma cells. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
Blr1 CRISPR/Cas9 KO Plasmid (h) - sc-402672 from Santa Cruz Biotechnology
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Blr1 HDR Plasmid (h) - sc-402672-HDR from Santa Cruz Biotechnology
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Blr1 Double Nickase Plasmid (h) - sc-402672-NIC from Santa Cruz Biotechnology
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Blr1 Double Nickase Plasmid (h2) - sc-402672-NIC-2 from Santa Cruz Biotechnology
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Blr1 CRISPR Activation Plasmid (h) - sc-402672-ACT from Santa Cruz Biotechnology
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Blr1 CRISPR Activation Plasmid (h2) - sc-402672-ACT-2 from Santa Cruz Biotechnology
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Blr1 Lentiviral Activation Particles (h) - sc-402672-LAC from Santa Cruz Biotechnology
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Blr1 Lentiviral Activation Particles (h2) - sc-402672-LAC-2 from Santa Cruz Biotechnology
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Blr1 siRNA (h) - sc-29812 from Santa Cruz Biotechnology
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Blr1 shRNA Plasmid (h) - sc-29812-SH from Santa Cruz Biotechnology
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Blr1 shRNA (h) Lentiviral Particles - sc-29812-V from Santa Cruz Biotechnology
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CXCR5 RNAi - H00000643-R03 from Novus Biologicals
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MISSION® esiRNA - EHU033091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6813 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6813 from Sigma-Aldrich
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CXCR5 siRNA (Human) - CRH0439 from Cohesion Biosciences
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CXCR5 RNAi - H00000643-R04 from Novus Biologicals
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CXCR5 - MBS8237432 from MyBioSource
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shRNA set against Human CXCR5 (NM_001716.4) - SHH272301 from Creative biogene
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Human CXCR5 siRNA - orb260941 from Biorbyt
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CXCR5 shRNA Plasmid (Human) - CHH0439 from Cohesion Biosciences
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CXCR5 miRNA 3'UTR clone - MiUTR3H-04249 from Creative biogene
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CXCR5 miRNA 3'UTR clone - MiUTR3H-04250 from Creative biogene
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