Gene Symbol | TRNT1 |
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Entrez Gene | 51095 |
Alt Symbol | CCA1, CGI-47, MtCCA, SIFD |
Species | Human |
Gene Type | protein-coding |
Description | tRNA nucleotidyl transferase, CCA-adding, 1 |
Other Description | CCA tRNA nucleotidyltransferase 1, mitochondrial|mitochondrial CCA-adding tRNA-nucleotidyltransferase|mt CCA-adding enzyme|mt tRNA CCA-diphosphorylase|mt tRNA CCA-pyrophosphorylase|mt tRNA adenylyltransferase|tRNA-nucleotidyltransferase 1, mitochondrial |
Swissprots | Q9Y362 Q9BS97 B7WP13 Q8ND57 C9JKA2 A8K2Z6 Q96Q11 |
Accessions | EAW63885 EAW63886 EAW63887 EAW63888 EAW63889 Q96Q11 AB063105 BAB70662 AF151805 AAD34042 AK124137 AK290411 BAF83100 AL834397 CAD39059 AM392669 CAL37547 AM393260 CAL38138 BC005184 AAH05184 BC012537 AAH12537 BQ722111 DA884423 DB032432 DB525237 EU832347 ACE87604 EU832432 ACE86917 XM_005265196 XP_005265253 XM_011533776 XP_011532078 XM_011533777 XP_011532079 XM_011533778 XP_011532080 XR_940445 XR_940446 NM_001302946 NP_001289875 NM_182916 NP_886552 NM_016000 |
Function | Isoform 1: Adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and ATP as substrates. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:11256614}. |
Top Pathways | RNA transport |
TRNT1 CRISPR/Cas9 KO Plasmid (h) - sc-405194 from Santa Cruz Biotechnology
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TRNT1 HDR Plasmid (h) - sc-405194-HDR from Santa Cruz Biotechnology
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TRNT1 Double Nickase Plasmid (h) - sc-405194-NIC from Santa Cruz Biotechnology
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TRNT1 Double Nickase Plasmid (h2) - sc-405194-NIC-2 from Santa Cruz Biotechnology
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TRNT1 CRISPR Activation Plasmid (h) - sc-405194-ACT from Santa Cruz Biotechnology
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TRNT1 CRISPR Activation Plasmid (h2) - sc-405194-ACT-2 from Santa Cruz Biotechnology
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TRNT1 Lentiviral Activation Particles (h) - sc-405194-LAC from Santa Cruz Biotechnology
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TRNT1 Lentiviral Activation Particles (h2) - sc-405194-LAC-2 from Santa Cruz Biotechnology
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TRNT1 siRNA (h) - sc-78516 from Santa Cruz Biotechnology
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TRNT1 shRNA Plasmid (h) - sc-78516-SH from Santa Cruz Biotechnology
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TRNT1 shRNA (h) Lentiviral Particles - sc-78516-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU091791 from Sigma-Aldrich
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MISSION® esiRNA - EHU099151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22047 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22047 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07330 from Sigma-Aldrich
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TRNT1 siRNA (Human) - CRH9516 from Cohesion Biosciences
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TRNT1 RNAi - H00051095-R01 from Novus Biologicals
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TRNT1 - MBS8223596 from MyBioSource
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shRNA set against Human TRNT1 (NM_182916.2) - SHH435416 from Creative biogene
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shRNA set against Human TRNT1(NM_182916.2) - SHG145855 from Creative biogene
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TRNT1 shRNA Plasmid (Human) - CHH9516 from Cohesion Biosciences
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TRNT1 miRNA 3'UTR clone - MiUTR1H-10776 from Creative biogene
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