Gene Symbol | PHEX |
---|---|
Entrez Gene | 5251 |
Alt Symbol | HPDR, HPDR1, HYP, HYP1, LXHR, PEX, XLH |
Species | Human |
Gene Type | protein-coding |
Description | phosphate regulating endopeptidase homolog, X-linked |
Other Description | X-linked hypophosphatemia protein|metalloendopeptidase homolog PEX|phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)|phosphate-regulating neutral endopeptidase|vitamin D-resistant hypophosphatemic rickets protein |
Swissprots | O00678 P78562 Q93032 Q99827 Q2M325 Q13646 |
Accessions | AAD08630 ACZ05046 CAA69326 CAA71258 CBX47539 EAW98987 P78562 AD000712 AAB51604 AK298030 BAG60332 AK301528 BAG63030 AK304551 BAG65346 BC105057 AAI05058 BC105059 AAI05060 BU680665 U60475 AAC50552 U75645 AAB47749 U82970 AAC24487 U87284 AAB47562 XM_011545533 XP_011543835 XM_011545534 XP_011543836 XM_011545535 XP_011543837 XM_011545536 XP_011543838 NM_000444 NP_000435 NM_001282754 NP_001269683 |
Function | Probably involved in bone and dentin mineralization and renal phosphate reabsorption. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Lymphocytes and fetal brain; not in adult brain, placenta, skeletal muscle and pancreas; not in adult and fetal heart, lung, liver and kidney. |
PHEX CRISPR/Cas9 KO Plasmid (h) - sc-408761 from Santa Cruz Biotechnology
|
||||||||
PHEX HDR Plasmid (h) - sc-408761-HDR from Santa Cruz Biotechnology
|
||||||||
PHEX Double Nickase Plasmid (h) - sc-408761-NIC from Santa Cruz Biotechnology
|
||||||||
PHEX Double Nickase Plasmid (h2) - sc-408761-NIC-2 from Santa Cruz Biotechnology
|
||||||||
PHEX CRISPR Activation Plasmid (h) - sc-408761-ACT from Santa Cruz Biotechnology
|
||||||||
PHEX CRISPR Activation Plasmid (h2) - sc-408761-ACT-2 from Santa Cruz Biotechnology
|
||||||||
PHEX Lentiviral Activation Particles (h) - sc-408761-LAC from Santa Cruz Biotechnology
|
||||||||
PHEX Lentiviral Activation Particles (h2) - sc-408761-LAC-2 from Santa Cruz Biotechnology
|
||||||||
PHEX siRNA (h) - sc-61334 from Santa Cruz Biotechnology
|
||||||||
PHEX shRNA Plasmid (h) - sc-61334-SH from Santa Cruz Biotechnology
|
||||||||
PHEX shRNA (h) Lentiviral Particles - sc-61334-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU057011 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN1710 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1710 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR03381 from Sigma-Aldrich
|
||||||||
PHEX siRNA (Human) - CRH3505 from Cohesion Biosciences
|
||||||||
PHEX RNAi - H00005251-R01 from Novus Biologicals
|
||||||||
shRNA set against Human PHEX (NM_000444.4) - SHH374584 from Creative biogene
|
||||||||
PHEX shRNA Plasmid (Human) - CHH3505 from Cohesion Biosciences
|
||||||||
PHEX miRNA 3'UTR clone - MiUTR3H-02837 from Creative biogene
|