Gene Symbol | ralb-a |
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Entrez Gene | 399338 |
Alt Symbol | Ral B, ralb, xralb |
Species | Xenopus |
Gene Type | protein-coding |
Description | v-ral simian leukemia viral oncogene homolog B |
Other Description | XRalB-A|ras-related protein ralB-A|v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) |
Swissprots | Q32N67 Q9YH09 |
Accessions | Q9YH09 BC108805 AAI08806 Y16259 CAA76143 NM_001090685 NP_001084154 |
Function | Regulates the actin cytoskeleton to play a role in gastrulation or neurulation. During the cleavage stages, the GTP- bound form induces a cortical reaction that affects the localization of pigment granules. Activated by the FGF pathway via ras and ral-GDS, but independently of raf. Directs ralbp1 to the plasma membrane. {ECO:0000269|PubMed:10328920, ECO:0000269|PubMed:14576358, ECO:0000269|PubMed:15511640}. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Tissue Specificity | Weakly expressed in adult tissues and highest levels were found in heart, brain and testes. {ECO:0000269|PubMed:10328920}. |
Recombinant Xenopus laevis Ras-related protein ralB-A(ralb-a) - CSB-YP897041XBE CSB-EP897041XBE CSB-BP897041XBE CSB-MP897041XBE from Cusabio
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Ras-related protein ralB-A (ralb-a), Recombinant Protein - MBS1411972 from MyBioSource
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