Gene Symbol | POU4F2 |
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Entrez Gene | 5458 |
Alt Symbol | BRN3.2, BRN3B, Brn-3b |
Species | Human |
Gene Type | protein-coding |
Description | POU class 4 homeobox 2 |
Other Description | Brn3b POU domain transcription factor|POU domain class 4 transcription factor 2|POU domain protein|POU domain, class 4, transcription factor 2|brain-3B|brain-specific homeobox/POU domain protein 3B |
Swissprots | B1PJR6 Q13883 B2RC84 Q14987 Q12837 |
Accessions | EAX05025 Q12837 AK314982 BAG37481 BC136344 AAI36345 BC136345 AAI36346 BY796838 DB082745 EU439706 ACA49233 L20434 AAA36393 U06233 AAA16509 X71488 CAA50589 NM_004575 NP_004566 |
Function | Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons. |
Subcellular Location | Nucleus speckle {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00530, ECO:0000269|PubMed:19266028}. |
Tissue Specificity | Brain. Seems to be specific to the retina. |
Brn-3b CRISPR/Cas9 KO Plasmid (h) - sc-400382 from Santa Cruz Biotechnology
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Brn-3b HDR Plasmid (h) - sc-400382-HDR from Santa Cruz Biotechnology
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Brn-3b Double Nickase Plasmid (h) - sc-400382-NIC from Santa Cruz Biotechnology
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Brn-3b Double Nickase Plasmid (h2) - sc-400382-NIC-2 from Santa Cruz Biotechnology
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Brn-3 CRISPR Activation Plasmid (h) - sc-400382-ACT from Santa Cruz Biotechnology
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Brn-3b CRISPR Activation Plasmid (h2) - sc-400382-ACT-2 from Santa Cruz Biotechnology
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Brn-3b Lentiviral Activation Particles (h) - sc-400382-LAC from Santa Cruz Biotechnology
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Brn-3b Lentiviral Activation Particles (h2) - sc-400382-LAC-2 from Santa Cruz Biotechnology
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Brn-3b siRNA (h) - sc-38766 from Santa Cruz Biotechnology
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Brn-3b shRNA Plasmid (h) - sc-38766-SH from Santa Cruz Biotechnology
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Brn-3b shRNA (h) Lentiviral Particles - sc-38766-V from Santa Cruz Biotechnology
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BRN3B/POU4F2 RNAi - H00005458-R01 from Novus Biologicals
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MISSION® esiRNA - EHU026321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17182 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17182 from Sigma-Aldrich
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POU4F2 siRNA (Human) - CRH3660 from Cohesion Biosciences
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shRNA set against Human POU4F2(NM_004575.2) - SHR129824 from Creative biogene
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Brn-3b CRISPR/Cas9 KO Plasmid (h2) - sc-400382-KO-2 from Santa Cruz Biotechnology
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Brn-3b HDR Plasmid (h2) - sc-400382-HDR-2 from Santa Cruz Biotechnology
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Human POU4F2 siRNA - orb264162 from Biorbyt
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POU4F2 shRNA Plasmid (Human) - CHH3660 from Cohesion Biosciences
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POU4F2 miRNA 3'UTR clone - MiUTR1H-08115 from Creative biogene
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