Gene Symbol | DNTTIP1 |
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Entrez Gene | 116092 |
Alt Symbol | C20orf167, Tdif1, dJ447F3.4 |
Species | Human |
Gene Type | protein-coding |
Description | deoxynucleotidyltransferase, terminal, interacting protein 1 |
Other Description | TdT binding protein|deoxynucleotidyltransferase terminal-interacting protein 1|tdT-interacting factor 1|terminal deoxynucleotidyltransferase-interacting factor 1 |
Swissprots | Q9H147 Q9H148 B2RA18 Q96DE3 Q9BQP2 |
Accessions | EAW75810 EAW75811 EAW75812 Q9H147 AB035676 BAB62888 AI538721 AK314003 BAG36715 BC009535 AAH09535 BC024290 AAH24290 BG720866 CD678110 HQ447713 ADQ32198 NM_052951 NP_443183 |
Function | Shown to enhance TdT activity, in vitro. Also acts as a transcriptional regulator, binding to the consensus sequence 5'- GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. {ECO:0000269|PubMed:11473582, ECO:0000269|PubMed:23874396}. |
Subcellular Location | Nucleus. |
TdTIF1 CRISPR/Cas9 KO Plasmid (h) - sc-409357 from Santa Cruz Biotechnology
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TdTIF1 HDR Plasmid (h) - sc-409357-HDR from Santa Cruz Biotechnology
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TdTIF1 Double Nickase Plasmid (h) - sc-409357-NIC from Santa Cruz Biotechnology
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TdTIF1 Double Nickase Plasmid (h2) - sc-409357-NIC-2 from Santa Cruz Biotechnology
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TdTIF1 CRISPR Activation Plasmid (h) - sc-409357-ACT from Santa Cruz Biotechnology
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TdTIF1 CRISPR Activation Plasmid (h2) - sc-409357-ACT-2 from Santa Cruz Biotechnology
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TdTIF1 Lentiviral Activation Particles (h) - sc-409357-LAC from Santa Cruz Biotechnology
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TdTIF1 Lentiviral Activation Particles (h2) - sc-409357-LAC-2 from Santa Cruz Biotechnology
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TdTIF1 siRNA (h) - sc-76640 from Santa Cruz Biotechnology
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TdTIF1 shRNA Plasmid (h) - sc-76640-SH from Santa Cruz Biotechnology
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TdTIF1 shRNA (h) Lentiviral Particles - sc-76640-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU047581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7410 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7410 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01199 from Sigma-Aldrich
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DNTTIP1 siRNA (Human) - CRJ4484 from Cohesion Biosciences
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DNTTIP1 - MBS8232710 from MyBioSource
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shRNA set against Human DNTTIP1 (NM_052951.2) - SHH280073 from Creative biogene
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shRNA set against Human DNTTIP1(NM_052951.2) - SHH012845 from Creative biogene
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DNTTIP1 shRNA Plasmid (Human) - CHJ4484 from Cohesion Biosciences
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DNTTIP1 miRNA 3'UTR clone - MiUTR1H-02948 from Creative biogene
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