| Gene Symbol |
CBS
|
| Entrez Gene |
100008766
|
| Alt Symbol |
-
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
cystathionine-beta-synthase
|
| Other Description |
beta-thionase|cystathionine beta-synthase|serine sulfhydrase
|
| Swissprots |
Q9N0V7
|
| Accessions |
CBF70965 CBF86258 CBF88762 CBF95147 CBF99433 CBG07460 CBU94986 CBV02092 CBV03187 CBV08667 CBV12953 CBV20982 Q9N0V7 AF248039 AAF64226 NM_001082082 NP_001075551
|
| Function |
Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
|
| Top Pathways |
Glycine, serine and threonine metabolism, Cysteine and methionine metabolism, Biosynthesis of amino acids
|