Gene Symbol | smug1 |
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Entrez Gene | 399139 |
Alt Symbol | xsmug1 |
Species | Xenopus |
Gene Type | protein-coding |
Description | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
Other Description | single-strand selective monofunctional uracil DNA glycosylase |
Swissprots | Q9YGN6 |
Accessions | Q9YGN6 AF125181 AAD17300 BC090216 AAH90216 NM_001090356 NP_001083825 |
Function | Responsible for recognizing base lesions in the genome and initiating base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA and has a preference for single-stranded DNA substrates. No enzymatic activity towards G/T mismatches. {ECO:0000269|PubMed:10074426}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Top Pathways | Base excision repair |
Recombinant Xenopus laevis Single-strand selective monofunctional uracil DNA gl - CSB-YP896645XBE CSB-EP896645XBE CSB-BP896645XBE CSB-MP896645XBE from Cusabio
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Single-strand selective monofunctional uracil DNA glycosylase (smug1), Recombinant Protein - MBS1398981 from MyBioSource
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