| Gene Symbol | PLK5 |
|---|---|
| Entrez Gene | 126520 |
| Alt Symbol | PLK-5, PLK5P, SgK384ps |
| Species | Human |
| Gene Type | protein-coding |
| Description | polo-like kinase 5 |
| Other Description | inactive serine/threonine-protein kinase PLK5|polo-like kinase 5, pseudogene |
| Swissprots | B3KNR4 Q1ZYM0 Q496M5 |
| Accessions | Q496M5 AI651075 AK054808 BAG51426 AK122648 BAG53640 BC100791 BC100792 BC100793 BF364682 DA058511 DQ424898 ABD83663 NM_001011716 NR_026557 NM_001243079 NP_001230008 |
| Function | Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation. {ECO:0000269|PubMed:21245385}. |
| Subcellular Location | Nucleus, nucleolus {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:21245385}. |
| Tissue Specificity | Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in the liver, and some cells in the germinal center of lymph nodes (at protein level). {ECO:0000269|PubMed:21245385}. |
MISSION® esiRNA - EHU150421 from Sigma-Aldrich
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MISSION® siRNA - SIHK1757 from Sigma-Aldrich
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MISSION® siRNA - SIHK1756 from Sigma-Aldrich
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MISSION® siRNA - SIHK1759 from Sigma-Aldrich
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MISSION® siRNA - SIHK1760 from Sigma-Aldrich
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MISSION® siRNA - SIHK1755 from Sigma-Aldrich
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MISSION® siRNA - SIHK1754 from Sigma-Aldrich
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MISSION® siRNA - SIHK1758 from Sigma-Aldrich
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MISSION® siRNA - SIHK1753 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16990 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16990 from Sigma-Aldrich
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PLK5 siRNA (Human) - CRJ4870 from Cohesion Biosciences
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shRNA set against Human Plk5 (NM_001243079.1) - SHH377940 from Creative biogene
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PLK5 shRNA Plasmid (Human) - CHJ4870 from Cohesion Biosciences
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