| Gene Symbol |
VNN3
|
| Entrez Gene |
55350
|
| Alt Symbol |
HSA238982
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vanin 3
|
| Other Description |
pantetheinase pseudogene|pantetheinase-associated gene expressed in leukocytes (PAGEL)-alpha|vanin 1 pseudogene|vanin-3|vascular non-inflammatory molecule 3
|
| Swissprots |
Q9BQY2 B2DFY1 B2DFY7 B2DFY8 Q3SX90 Q9NY84 B2DFY0 B2DFY3 B2DFY6 B2DFY5
|
| Accessions |
ABA60895 EAW48017 EAW48018 EAW48019 Q9NY84 AA461448 AA461622 AB435052 BAG30924 AB435053 BAG30925 AB435054 BAG30926 AB435055 BAG30927 AB435056 BAG30928 AB435057 BAG30929 AB435058 BAG30930 AB435059 BAG30931 AB435060 BAG30932 AB435061 BAG30933 AJ238982 CAB76824 AK075110 AK314708 BAG37255 BC104416 AAI04417 BC104417 AAI04418 BC113022 AAI13023 BC113023 AAI13024 BC148317 AAI48318 DA670661 NM_001291702 NP_001278631 NM_001291703 NP_001278632 NM_018399 NM_078625
|
| Function |
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. {ECO:0000269|PubMed:11491533}.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}. Note=According to PubMed:11491533, secreted. {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed with higher expression in liver and blood. Expressed in differentiated keratinocytes in epidermis and in epithelial cells in dermis. Overexpressed in lesional psoriatic skin. {ECO:0000269|PubMed:11491533, ECO:0000269|PubMed:19322213}.
|
![Western Blot: VNN3 Overexpression Lysate (Adult Normal) [NBL1-17733] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for VNN3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6847_VNN3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17733-img0002.jpg)