| Gene Symbol |
CNNM2
|
| Entrez Gene |
54805
|
| Alt Symbol |
ACDP2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cyclin and CBS domain divalent metal cation transport mediator 2
|
| Other Description |
ancient conserved domain-containing protein 2|cyclin M2|metal transporter CNNM2
|
| Swissprots |
Q9NRK5 Q9H952 Q5T569 Q9H8M5 Q9NXT4 Q8WU59 Q5T570
|
| Accessions |
EAW49659 EAW49660 EAW49661 EAW49662 EAW49663 EAW49664 Q9H8M5 AF216962 AAF86374 AK000071 BAA90926 AK023066 BAB14386 AK023479 BAB14585 AK090785 BC021222 AAH21222 BU621540 BX113753 XM_005269933 XP_005269990 XM_006717908 XP_006717971 XM_011539911 XP_011538213 XR_945780 XR_945781 XR_945782 NM_017649 NP_060119 NM_199076 NP_951058 NM_199077 NP_951059
|
| Function |
Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed. Expressed at higher level in brain, kidney and placenta, while it is weakly expressed in skeletal muscle. In the kidney, it is expressed in the distal convoluted tubule and the thick ascending limb of Henle loop. {ECO:0000269|PubMed:21397062}.
|