GABRA2
| Gene Symbol | GABRA2 |
|---|---|
| Entrez Gene | 2555 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| Other Description | GABA(A) receptor subunit alpha-2|GABA(A) receptor, alpha 2|gamma-aminobutyric acid receptor subunit alpha-2 |
| Swissprots | Q59G14 B7Z1H8 A8K0U7 P47869 |
| Accessions | AAY40994 EAW93022 EAW93023 EAW93024 EAW93025 P47869 A28100 CAA01918 AB209295 BAD92532 AF086092 AK125179 BAG54159 AK289662 BAF82351 AK293466 BAH11514 AK307128 BC022488 AAH22488 BX108394 DB478542 DN991770 HG496881 JF432507 ADZ15724 S62907 AAB27278 XM_005248080 XP_005248137 XM_011513675 XP_011511977 XM_011513676 XP_011511978 NM_000807 NP_000798 NM_001114175 NP_001107647 NM_001286827 NP_001273756 |
| Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. |
| Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |
GABA A Rα2 CRISPR/Cas9 KO Plasmid (h) - sc-402715 from Santa Cruz Biotechnology
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GABA A Rα2 HDR Plasmid (h) - sc-402715-HDR from Santa Cruz Biotechnology
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GABA A Rα2 Double Nickase Plasmid (h) - sc-402715-NIC from Santa Cruz Biotechnology
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GABA A Rα2 Double Nickase Plasmid (h2) - sc-402715-NIC-2 from Santa Cruz Biotechnology
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GABA A Rα2 CRISPR Activation Plasmid (h) - sc-402715-ACT from Santa Cruz Biotechnology
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GABA A Rα2 CRISPR Activation Plasmid (h2) - sc-402715-ACT-2 from Santa Cruz Biotechnology
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GABA A Rα2 Lentiviral Activation Particles (h) - sc-402715-LAC from Santa Cruz Biotechnology
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GABA A Rα2 Lentiviral Activation Particles (h2) - sc-402715-LAC-2 from Santa Cruz Biotechnology
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GABA A Rα2 siRNA (h) - sc-42427 from Santa Cruz Biotechnology
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GABA A Rα2 shRNA Plasmid (h) - sc-42427-SH from Santa Cruz Biotechnology
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GABA A Rα2 shRNA (h) Lentiviral Particles - sc-42427-V from Santa Cruz Biotechnology
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GABA-A R alpha 2 RNAi - H00002555-R01 from Novus Biologicals
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MISSION® esiRNA - EHU080531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1819 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1819 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04987 from Sigma-Aldrich
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GABRA2 siRNA (Human) - CRH1693 from Cohesion Biosciences
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GABRA2 - MBS8236568 from MyBioSource
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GABAA Rα2 CRISPR/Cas9 KO Plasmid (h2) - sc-402715-KO-2 from Santa Cruz Biotechnology
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GABAA Rα2 HDR Plasmid (h2) - sc-402715-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human GABRA2 (NM_000807.2) - SHH298449 from Creative biogene
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shRNA set against Human GABRA2(NM_000807.2) - SHH073721 from Creative biogene
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GABRA2 shRNA Plasmid (Human) - CHH1693 from Cohesion Biosciences
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GABRA2 miRNA 3'UTR clone - MiUTR1H-03910 from Creative biogene
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GABRA2 miRNA 3'UTR clone - MiUTR3H-00845 from Creative biogene
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