Gene Symbol | MRPL14 |
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Entrez Gene | 64928 |
Alt Symbol | L14mt, L32mt, MRP-L14, MRP-L32, MRPL32, RMPL32, RPML32 |
Species | Human |
Gene Type | protein-coding |
Description | mitochondrial ribosomal protein L14 |
Other Description | 39S ribosomal protein L14, mitochondrial|39S ribosomal protein L32, mitochondrial |
Swissprots | Q96Q72 B2R575 Q6P1L8 |
Accessions | BAB54929 EAX04242 EAX04243 EAX04244 EAX04245 Q6P1L8 AA758781 AK312086 BAG35022 BC010416 BC065005 AAH65005 BM559405 BM910935 HQ448655 ADQ33133 XM_005249299 XP_005249356 XM_005249300 XP_005249357 XM_005249301 XP_005249358 XM_011514814 XP_011513116 NM_032111 NP_115487 |
Function | Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable). {ECO:0000305|PubMed:22829778}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:11543634, ECO:0000269|PubMed:22829778}. |
Top Pathways | Ribosome |
MRP-L14 CRISPR/Cas9 KO Plasmid (h) - sc-413058 from Santa Cruz Biotechnology
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MRP-L14 HDR Plasmid (h) - sc-413058-HDR from Santa Cruz Biotechnology
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MRP-L14 Double Nickase Plasmid (h) - sc-413058-NIC from Santa Cruz Biotechnology
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MRP-L14 Double Nickase Plasmid (h2) - sc-413058-NIC-2 from Santa Cruz Biotechnology
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MRP-L14 CRISPR Activation Plasmid (h) - sc-413058-ACT from Santa Cruz Biotechnology
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MRP-L14 CRISPR Activation Plasmid (h2) - sc-413058-ACT-2 from Santa Cruz Biotechnology
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MRP-L14 Lentiviral Activation Particles (h) - sc-413058-LAC from Santa Cruz Biotechnology
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MRP-L14 Lentiviral Activation Particles (h2) - sc-413058-LAC-2 from Santa Cruz Biotechnology
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MRP-L14 siRNA (h) - sc-95086 from Santa Cruz Biotechnology
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MRP-L14 shRNA Plasmid (h) - sc-95086-SH from Santa Cruz Biotechnology
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MRP-L14 shRNA (h) Lentiviral Particles - sc-95086-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU136931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14549 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14549 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00816 from Sigma-Aldrich
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MRPL14 siRNA (Human) - CRJ2144 from Cohesion Biosciences
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shRNA set against Human Mrpl14 (NM_032111.2) - SHH344556 from Creative biogene
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shRNA set against Human MRPL14(NM_032111.2) - SHH199343 from Creative biogene
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MRPL14 shRNA Plasmid (Human) - CHJ2144 from Cohesion Biosciences
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MRPL14 miRNA 3'UTR clone - MiUTR1H-06428 from Creative biogene
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