Gene Symbol | CEP57 |
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Entrez Gene | 9702 |
Alt Symbol | MVA2, PIG8, TSP57 |
Species | Human |
Gene Type | protein-coding |
Description | centrosomal protein 57kDa |
Other Description | FGF2-interacting protein|centrosomal protein of 57 kDa|proliferation-inducing protein 8|testis-specific protein 57|translokin |
Swissprots | Q8IXP0 Q14704 A8K5D0 Q5JB46 Q86XR8 F5H5F7 Q9BVF9 B4DDP5 A0PJH1 |
Accessions | EAW66965 EAW66966 EAW66967 EAW66968 EAW66969 EAW66970 Q86XR8 AA730219 AK098647 AK125164 AK291245 BAF83934 AK293277 BAG56806 AY225092 AAO73938 AY239292 AAP72184 BC001233 AAH01233 BC009053 BC029385 AAH29385 BC031048 BC039711 AAH39711 BG699097 D42054 BAA07654 DB032301 XM_006718945 XP_006719008 XM_006718946 XP_006719009 NM_001243776 NP_001230705 NM_001243777 NP_001230706 NM_014679 NP_055494 |
Function | Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring- like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1. {ECO:0000269|PubMed:22321063}. |
Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12717444}. |
CEP57 CRISPR/Cas9 KO Plasmid (h) - sc-416340 from Santa Cruz Biotechnology
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CEP57 HDR Plasmid (h) - sc-416340-HDR from Santa Cruz Biotechnology
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CEP57 Double Nickase Plasmid (h) - sc-416340-NIC from Santa Cruz Biotechnology
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CEP57 Double Nickase Plasmid (h2) - sc-416340-NIC-2 from Santa Cruz Biotechnology
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CEP57 CRISPR Activation Plasmid (h) - sc-416340-ACT from Santa Cruz Biotechnology
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CEP57 CRISPR Activation Plasmid (h2) - sc-416340-ACT-2 from Santa Cruz Biotechnology
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CEP57 Lentiviral Activation Particles (h) - sc-416340-LAC from Santa Cruz Biotechnology
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CEP57 Lentiviral Activation Particles (h2) - sc-416340-LAC-2 from Santa Cruz Biotechnology
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CEP57 siRNA (h) - sc-96282 from Santa Cruz Biotechnology
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CEP57 shRNA Plasmid (h) - sc-96282-SH from Santa Cruz Biotechnology
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CEP57 shRNA (h) Lentiviral Particles - sc-96282-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU082651 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5969 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5969 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09456 from Sigma-Aldrich
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CEP57 siRNA (Human) - CRH6473 from Cohesion Biosciences
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CEP57 RNAi - H00009702-R01 from Novus Biologicals
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CEP57 - MBS8204521 from MyBioSource
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shRNA set against Human CEP57 (NM_014679.4) - SHH261933 from Creative biogene
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Human CEP57 siRNA - orb266975 from Biorbyt
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CEP57 shRNA Plasmid (Human) - CHH6473 from Cohesion Biosciences
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CEP57 miRNA 3'UTR clone - MiUTR3H-09601 from Creative biogene
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