Gene Symbol | Serpine1 |
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Entrez Gene | 18787 |
Alt Symbol | PAI-1, PAI1, Planh1 |
Species | Mouse |
Gene Type | protein-coding |
Description | serine (or cysteine) peptidase inhibitor, clade E, member 1 |
Other Description | PAI|Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI)|endothelial plasminogen activator inhibitor|nexin, plasminogen activator inhibitor type 1|plasminogen activator inhibitor 1|plasminogen activator inhibitor, type I|serine (or cysteine) proteinase inhibitor, clade E, member 1|serpin E1 |
Swissprots | P22777 |
Accessions | EDL19286 EDL19287 P22777 AK040662 BC054091 AAH54091 GQ872458 ACX48997 GQ872459 ACX48998 M33960 AAA39887 NM_008871 NP_032897 |
Function | Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Top Pathways | p53 signaling pathway, Complement and coagulation cascades, Chagas disease (American trypanosomiasis), Hippo signaling pathway |
Mouse PAI1 + PLAT full length protein - ab92709 from Abcam
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Mouse SERPIN E1 protein - orb180373 from Biorbyt
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SERPINE1 / PAI1 (Wild type) - AR31009PU-N from Acris Antibodies
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Mouse PAI-1, Recombinant - 227-10207 from RayBiotech
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Recombinant Mouse Serpine1 - Serpine1-2462M from Creative Biomart
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Recombinant Mouse Serine (or cysteine) Peptidase Inhibitor, Clade E, Member 1 - Serpine1-5319M from Creative Biomart
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Recombinant Mouse Serine (or cysteine) Peptidase Inhibitor, Clade E, Member 1 - Serpine1-5282M from Creative Biomart
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Mouse PAI-1 tPA complex - MPAI-TPA from Molecular Innovations
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Glycosylated Mouse PAI-1 (stable mutant) - GLYMPAI-I91L from Molecular Innovations
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Mouse PAI-1 (Biotin labeled active fraction) - MPAI-BIO from Molecular Innovations
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Mouse PAI-1 (Biotin labeled latent fraction) - MPAI-L-BIO from Molecular Innovations
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Mouse PAI-1 (stable mutant) - MPAI-I91L from Molecular Innovations
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Mouse PAI-1 (wild type active fraction) - MPAI from Molecular Innovations
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Mouse PAI-1 (wild type latent form) - MPAI-L from Molecular Innovations
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Mouse PAI-1 genetically deficient brain - MPAI-KO-BR from Molecular Innovations
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Mouse PAI-1 genetically deficient heart - MPAI-KO-HT from Molecular Innovations
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Mouse PAI-1 genetically deficient kidney - MPAI-KO-KD from Molecular Innovations
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Mouse PAI-1 genetically deficient liver - MPAI-KO-LR from Molecular Innovations
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Mouse PAI-1 genetically deficient lung - MPAI-KO-LG from Molecular Innovations
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Mouse PAI-1 genetically deficient plasma, sodium citrate - MPAI-KO-SC from Molecular Innovations
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Mouse PAI-1 genetically deficient spleen - MPAI-KO-SP from Molecular Innovations
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Mouse PAI-1 N-terminal biotin labeled stable mutant - NTBIOMPAI-I91L from Molecular Innovations
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Recombinant Plasminogen Activator Inhibitor 1 (PAI1) - RPA532Mu01 from Cloud-clone
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Recombinant Plasminogen Activator Inhibitor 1 (PAI1) - RPA532Mu02 from Cloud-clone
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Recombinant Mouse Plasminogen activator inhibitor 1(Serpine1) - CSB-YP021081MO CSB-EP021081MO CSB-BP021081MO CSB-MP021081MO from Cusabio
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