Gene Symbol |
CPOX
|
Entrez Gene |
1371
|
Alt Symbol |
CPO, CPX, HCP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
coproporphyrinogen oxidase
|
Other Description |
COX|coprogen oxidase|coproporphyrinogen-III oxidase, mitochondrial|coproporphyrinogenase|oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
|
Swissprots |
Q53F08 A8K275 Q14060 Q96AF3 B4DSD5 P36551 Q8IZ45
|
Accessions |
CAA84292 EAW79854 P36551 AK223481 BAD97201 AK290140 BAF82829 AK299692 BAG61597 BC017210 AAH17210 BC023551 AAH23551 BC023554 AAH23554 BX648974 D16611 BAA04033 Z28409 CAA82250 XM_005247125 XP_005247182 XM_011512437 XP_011510739 NM_000097 NP_000088
|
Function |
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
|
Subcellular Location |
Mitochondrion intermembrane space.
|
Top Pathways |
Porphyrin and chlorophyll metabolism
|