| Gene Symbol | FUT9 |
|---|---|
| Entrez Gene | 10690 |
| Alt Symbol | Fuc-TIX |
| Species | Human |
| Gene Type | protein-coding |
| Description | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) |
| Other Description | alpha-(1,3)-fucosyltransferase 9|fucT-IX|fucosyltransferase IX|galactoside 3-L-fucosyltransferase |
| Swissprots | Q9Y231 Q5T0W4 |
| Accessions | EAW48510 EAW48511 Q9Y231 AB023021 BAA81685 AJ238701 CAB41890 AK095046 AK293817 BAG57222 AK314966 BAG37467 AL080093 AL833558 AY800264 AAV67966 BC001879 AAH01879 BC036101 AAH36101 CK299829 CK904220 DQ894123 ABM85049 XM_011535383 XP_011533685 XM_011535384 XP_011533686 XM_011535385 XP_011533687 NM_006581 NP_006572 |
| Function | Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. {ECO:0000269|PubMed:10386598}. |
| Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000250}. |
| Tissue Specificity | Strongly expressed in forebrain and stomach, lower expression in spleen and peripheral blood leukocytes, and no expression in small intestine, colon, liver, lung, kidney, adrenal cortex or uterus. {ECO:0000269|PubMed:10386598}. |
| Top Pathways | Other types of O-glycan biosynthesis, Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series |